040-000-530 Sacubitril Sodium
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| Type | Active Pharmaceutical ingredient |
| Synonym | AHU377 |
| CAS No. | 149690-05-1 |
| Chemical Formula | C24H28NNaO5 |
| Appearance | white powder |
| Packaging | 200mg, 500mg, 1g, 5g, 10g |
| Assay | ≥98% |
| Related Products | Valsartan, Irbesartan, Olmesartan Medoxomil |
Description
Description
Sacubitril Sodium Introduction
Sacubitril Sodium, also known as AHU377, is an angiotensin receptor neprilysin inhibitor being studied for use in combination with valsartan for heart failure. Sacubitril is a prodrug that is activated to LBQ657 by de-ethylation via esterases. LBQ657 inhibits the enzyme neprilysin, which is responsible for the degradation of atrial and brain natriuretic peptides, two blood pressure lowering peptides that work mainly by reducing blood volume.
Sacubitril Sodium Specification
| Appearance | white powder |
| Melting Point | 163-165℃ |
| Content | 99.0% |
| Packaging | 200mg, 500mg, 1g, 5g, 10g |
Sacubitril Sodium Applications
Sacubitril Sodium, also known as AHU377, is an angiotensin receptor neprilysin inhibitor being studied for use in combination with valsartan for heart failure.
