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040-000-530 Sacubitril Sodium

Sacubitril Sodium, AHU377
SKU: 040-000-530 Category:
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Type Active Pharmaceutical ingredient
Synonym AHU377
CAS No. 149690-05-1
Chemical Formula C24H28NNaO5
Appearance white powder
Packaging 200mg, 500mg, 1g, 5g, 10g
Assay ≥98%
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Description

Description

Sacubitril Sodium Introduction

Sacubitril Sodium, also known as AHU377, is an angiotensin receptor neprilysin inhibitor being studied for use in combination with valsartan for heart failure. Sacubitril is a prodrug that is activated to LBQ657 by de-ethylation via esterases. LBQ657 inhibits the enzyme neprilysin, which is responsible for the degradation of atrial and brain natriuretic peptides, two blood pressure lowering peptides that work mainly by reducing blood volume.

Sacubitril Sodium Specification

Appearance white powder
Melting Point 163-165℃
Content 99.0%
Packaging 200mg, 500mg, 1g, 5g, 10g

 

Sacubitril Sodium Applications

Sacubitril Sodium, also known as AHU377, is an angiotensin receptor neprilysin inhibitor being studied for use in combination with valsartan for heart failure.

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