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040-000-294 Oseltamivir Phosphate, CAS 204255-11-8

oseltamivir phosphate
SKU: 040-000-294 Category:
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Synonym 4R-(acetylamino)-5S-amino-3R-(1-ethylpropoxy)-1-cyclohexene-1-carboxylic acid, ethyl ester, monophosphate
Type Neuaminidase inhibitor
Keywords Neuaminidase, influenza
Related products Arbidol Hydrochloride, Oseltamivir Acid, Sirolimus
Description

Description

Oseltamivir Phosphate Specifications

Product Name Oseltamivir Phosphate
CAS Registry Number 204255-11-8
Molecular Formula C16H28N2O4 • H3PO4
Molecular Weight 410.4 g/mol
Purity 98 %
Appearance White crystalline powder
Package 1kg-25kg
Shelf life 2 years
Functions inhibitor of neuraminidase, treating influenza

Oseltamivir Phosphate Description

Oseltamivir is a specific inhibitor of neuraminidase. Its inhibitory effect on neuraminidase can inhibit the mature influenza virus from detaching from host cells, thereby inhibiting the spread of the influenza virus in the human body to play a role in treating influenza. Oseltamivir acid is the active metabolite of oseltamivir.

Tamiflu (oseltamivir phosphate) is an oral antiviral drug approved for the treatment of acute, uncomplicated influenza in patients 2 weeks of age and older whose flu symptoms have not lasted more than two days.

oseltamivir phosphate

oseltamivir phosphate

Oseltamivir Phosphate Applications

  • Pharmaceutical anti-flu drugs
  • Laboratory research

Reference:

  1. Sidwell, R.W., Huffman, J.H., Barnard, D.L., et al. Inhibition of influenza virus infections in mice by GS4104, an orally effective influenza virus neuraminidase inhibitor. Antiviral Res. 37(2), 107-120 (1998).
  2. Hayden, F.G., Atmar, R.L., Schilling, M., et al. Use of the selective oral neuraminidase inhibitor oseltamivir to prevent influenza. New England Journal of Medicine 341(18), 1336-1343 (1999).
  3. Li, W., Escarpe, P.S., Eisenberg, E.J., et al. Identification of GS 4104 as an orally bioavailable prodrug of the influenza virus neuraminidase inhibitor GS 4071. Antimicrobial Agents and Chemotherapy 42(3), 647-653 (1998).
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