070-000-252 Matrixyl Peptide, CAS: 214047-00-4

Description

Matrixyl Peptide Specifications

Matrixyl Peptide Description

Matrixyl peptide, also called palmitoyl pentapeptide-4, is an artificial ingredient in cosmetics. It can stimulate the production of collagen, and elastin, and reduce the appearance of fine lines and wrinkles. It is generally considered to be safe.

Benefits of Matrixyl Peptide to the Skin:

• Stimulating Collagen Synthesis: Matrixyl can induce fibroblasts in the skin to increase collagen synthesis in order to regain the elasticity and firmness of the skin and erode minute wrinkles and lines.
• Enhances Skin Elasticity: With the stimulation of elastin, Matrixyl increases the elasticity of the skin, and consequently, the skin becomes firmer and radiant.
• Smothes Wrinkles and Fine Lines: By increasing the amount of elastin and collagen, Matrixyl effectively reduces facial wrinkles and fine lines, particularly expression lines on the eyes and forehead.
• Repairs the Skin Barrier: Matrixyl reinforces the natural barrier function of the skin, enhancing its ability to retain moisture and leaving the skin softer and smoother.
• Improves Skin Texture: With regular use of Matrixyl, the skin can become finer and smoother, reducing roughness and the appearance of large pores.
• Anti-Aging: As we age, the elastin and collagen in the skin gradually run out. Matrixyl slows down the process of skin aging by inducing the production of these vital proteins.
• Gentle and Low-Irritation: Matrixyl is a gentle product that may be applied on most skin types, including sensitive skin, and is not prone to causing irritation or allergic reactions.

Mechanism of Matrixyl Peptide

Matrixyl works by mimicking naturally occurring peptide signaling molecules in the body, which inform skin cells to synthesize collagen and elastin. It also inhibits enzymes (such as matrix metalloproteinases) that break down collagen, protecting the skin’s collagen from excessive breakdown.

Matrixyl Peptide Applications

• Cosmetic ingredient

Reference

1. Giangreco F, Höfinger S, Bakalis E, Zerbetto F. Impact of the green tea ingredient epigallocatechin gallate and a short pentapeptide (Ile-Ile-Ala-Glu-Lys) on the structural organization of mixed micelles and the related uptake of cholesterol. Biochim Biophys Acta Gen Subj. 2018 Sep;1862(9):1956-1963. doi: 10.1016/j.bbagen.2018.06.005. Epub 2018 Jun 15.
2. 5: Kamiya M, Oyauchi K, Sato Y, Yokoyama T, Wang M, Aizawa T, Kumaki Y, Mizuguchi M, Imai K, Demura M, Suzuki K, Kawano K. Structure-activity relationship of a novel pentapeptide with cancer cell growth-inhibitory activity. J Pept Sci. 2010 May;16(5):242-8. doi: 10.1002/psc.1225.
3. Romanowski M, Zhu X, Ramaswami V, Misicka A, Lipkowski AW, Hruby VJ, O’Brien DF. Interaction of a highly potent dimeric enkephalin analog, biphalin, with model membranes. Biochim Biophys Acta. 1997 Oct 23;1329(2):245-58.