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040-000-335 Dasatinib Monohydrate, CAS 863127-77-9

dasatinib monohydrate
SKU: 040-000-335 Category:
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Synonyms Dasatinib hydrate; N-[2-Chloro-6-methylphenyl]-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-5-thiazolecarboxamide;
Keywords Anti-aging, cancer, remove senescent cells, treatment of leukemia
Related products Metformin (Hydrochloride), Berberine, Acarbose
Description

Description

Dasatinib Monohydrate Specifications

Product Name Dasatinib Monohydrate
CAS Registry Number 863127-77-9
Molecular Formula C22H28ClN7O3S
Molecular Weight 506.02
Purity >97.0 %
Appearance White powder
Package 1kg-25kg
Shelf life 2 years
Functions Remove senescent cells, treatment of leukemia

Dasatinib Monohydrate Description

Dasatinib monohydrate is an inhibitor of Src family kinases, including c-Abl and Bcr-Abl tyrosine kinase activity. Dasatinib inhibits c-Abl and Bcr-Abl tyrosine kinase activity and shows efficacy against imatinib-resistant Bcr-Abl mutations.

Dasatinib monohydrate is a hydrate that is the monohydrate of dasatinib. It is used for the treatment of chronic, accelerated, or myeloid or lymphoid blast phase chronic myeloid leukemia.

dasatinib monohydrate

Pharmacological effects of Dasatinib Monohydrate

  • Antineoplastic drugs: Substances that inhibit or prevent tumor proliferation.
  • Tyrosine kinase inhibitor: Protein kinase inhibitors that inhibit tyrosine protein kinases.

Dasatinib Monohydrate Applications

  • Laboratory research
  • Used as a pharmaceutical ingredient of anti-cancer drugs

Reference:

  1. Hořínková J, Šíma M, Slanař O.Prague Med Rep. 2019;120(2-3):52-63.
  2. Shah NP.Drugs Today (Barc). 2007 Jan;43(1):5-12.
  3. Palmer AK, Xu M, Tchkonia T, Kirkland JL.Aging Cell. 2019 Jun;18(3):e12950. doi: 10.1111
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