040-000-337 Spermidine Trihydrochloride, CAS 334-50-9
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| Synonym | Spermidine |
| Keywords | Anti-aging, inhibit neuron synthetase, Alzheimer’s disease |
| Related products | β-Nicotinamide mononucleotide, NMN, Nicotinamide Riboside, NR, Dasatinib Monohydrate |
Description
Description
Spermidine Trihydrochloride Specifications
| Product Name | Spermidine |
| CAS Registry Number | 334-50-9 |
| Molecular Formula | C7H19N3 |
| Molecular Weight | 145.2 g/mol |
| Purity | 99 % |
| Appearance | White powder |
| Shelf life | 2 years |
| Functions | Induce phagocytosis, Retarded protein aging, Inhibition of neuronal NO synthase (nNOS) |
Spermidine Trihydrochloride Description
Spermidine, also known as Spermidine Trihydrochloride, is a polyamine. Spermidine Trihydrochloride is widely distributed in organisms and is biosynthesized by putrescine (butanediamine) and adenosylmethionine. Spermidine can inhibit neuron synthetase, bind, and precipitate DNA; it can also be used to purify DNA-binding proteins and stimulate T4 polynucleotide kinase activity.
Spermidine trihydrochloride is a polyamine that inhibits neuronal nitric oxide synthase (nNOS) and binds and precipitates DNA. It may be used to purify DNA binding proteins.
On September 1, 2013, German and Austrian scientists collaborated to show that spermidine may prevent Alzheimer’s disease.
Reference:
- Cull, M; McHenry, CS (1990). Preparation of extracts from prokaryotes. Methods in Enzymology. 182. pp. 147–53.
- Wu, WH; Morris, DR (1973). “Biosynthetic arginine decarboxylase from Escherichia coli. Subunit interactions and the role of magnesium ion”. The Journal of Biological Chemistry. 248 (5): 1696–9.
- Tabor, CW; Tabor, H (1984). “Polyamines”. Annual Review of Biochemistry. 53: 749–90.
