4-Bromopyrazole Introduction

4-Bromopyrazole is a pyrazole derivative, which is reported to react with titanium tetrachloride to afford binary adducts. Mutagenicity of 4-bromopyrazole has been tested using the L-arabinose forward mutation assay of Salmonella typhimurium. It is reported to inhibit oxidative phosphorylation, the ATP-32P exchange reaction, and energy-dependent and independent calcium uptake.

4-Bromopyrazole Applications

• Used in the preparation of 4-bromo-1-(2-chloroethyl)-1H-pyrazole. It may be used as starting material in the synthesis of 1,4′-bipyrazoles.
• Used in the preparation of solid hexacoordinate complexes by reaction with dimethyl- and divinyl-tindichloride.

4-Bromopyrazole Safety and Handling

GHS H Statement:
Causes serious eye irritation.
May cause respiratory irritation.
Causes skin irritation.

GHS P Statement:
Avoid breathing dust/fume/gas/mist/vapors/spray.
IF ON SKIN: Wash with plenty of soap and water.
Wear protective gloves/protective clothing/eye protection/face protection.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present, and easy to do. Continue rinsing. WARNING: The information provided on this website was developed in compliance with European Union (EU) regulations and is correct to the best of our knowledge, information, and belief at the date of its publication. The information given is designed only as a guide for safe handling and use. It is not to be considered as either a warranty or quality specification. GHS Signal Word: Warning