040-000-295 Peramivir, CAS 330600-85-6
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| Synonyms | (1S,2S,3R,4R)-3-[(1S)-1-(acetylamino)-2-ethylbutyl]-4-[(aminoiminomethyl)amino]-2-hydroxy-cyclopentanecarboxylic acid |
| Type | Neuraminidase |
| Keywords | Influenza, anti-virus |
| Related products | Piperaquine, Chloroquine Diphosphate, Artemisinin, Acrichin Dihydrochloride |
Description
Description
Peramivir Specifications
| Product Name | C15H28N4O4 |
| CAS Registry Number | 330600-85-6 |
| Molecular Formula | C15H28N4O4 |
| Molecular Weight | 324.8 g/mol |
| Purity | 99 % |
| Appearance | White crystalline solid |
| Package | 1kg-25kg |
| Shelf life | 2 years |
| Functions | Treating Influenza A and B |
Peramivir Description
Peramivir is an antiviral drug developed by BioCryst Pharmaceuticals for the treatment of influenza. It is selective for influenza neuraminidase over bacterial, mammalian, and other viral neuraminidases. Pretreatment with peramivir (10-100 mg/kg) protects mice against lethal influenza infections. It also increases survival in ferrets infected intranasally with avian influenza type A H5N1 when injected intramuscularly after infection. Formulations containing peramivir have been used to treat influenza.
Peramivir is an antiviral agent developed by Biocryst Pharmaceuticals to treat influenza A/B.
peramivir
Peramivir Applications
- Pharmaceutical anti-flu drugs
Reference:
- Young, D., Fowler, C., and Bush, K. RWJ-270201 (BCX-1812): A novel neuraminidase inhibitor for influenza. Philos. Trans. R. Soc. Lond. B Biol. Sci 356(1416), 1905-1913 (2001).
- Yun, N.E., Linde, N.S., Zacks, M.A., et al. Injectable peramivir mitigates disease and promotes survival in ferrets and mice infected with the highly virulent influenza virus, A/Vietnam/1203/04 (H5N1). Virology 374(1), 198-209 (2008).
