050-000-282 Chlorogenic Acid, CAS 327-97-9

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Synonyms 1,4,5-Trihydroxycyclohexanecarboxylic acid 3-(3,4-dihydroxycinnamate), 3-(3,4-Dihydroxycinnamoyl)quinic acid
Source Eucommia ulmoides
Keywords Liver, anti-oxidation, blood glucose, anti-cancer
Related products Monoammonium Glycyrrhizinate, Metformin (Hydrochloride), Silybum Marianum Extract
Description

Description

Specifications of Chlorogenic Acid

Product Name Chlorogenic Acid
CAS Registry Number 327-97-9
Molecular Formula C16H18O9
Molecular Weight 354.31
Purity 5-98 %
Appearance White to slightly yellowish-beige powder
Melting point 210 °C
Package 1kg-25kg
Shelf life 2 years
Functions Protect liver, gallbladder, anti-oxidation, anti-bacteria, anti-cancer,

Description of Chlorogenic Acid

Chlorogenic acid is an important intermediate in lignin biosynthesis. This compound, long known as an antioxidant, also slows the release of glucose into the bloodstream after a meal. The common sources of chlorogenic acid are Eucommia, coffee beans, and honeysuckle.

Chlorogenic Acid is a polyphenol and the ester of caffeic acid and quinic acid that is found in coffee and black tea, with potential antioxidant and chemopreventive activities.

Chlorogenic Acid has a broad antibacterial effect, advantageous bravery, hemostatic, increased white blood cells, and antiviral effects, the effect of the blood clotting and bleeding time is shortened.

chlorogenic acid

Chlorogenic Acid Benefits for Weight Loss

The presence of chlorogenic acid is a promising natural component for weight loss since the mechanism of action is not one-dimensional; it inhibits fat accumulation, regulates blood sugar level, enhances metabolism, and suppresses appetite.

1. Inhibition of Fat Accumulation
Because of its metabolic effects on fat and glucose, chlorogenic acid decreases the absorption of fats from the diet, leading to reduced fat content in the body. It is also believed to work on reducing the formation of new fat cells, a process called adipogenesis, which, over time, may contribute to a lowering of total body fat.

2. Regulation of Blood Sugar Levels

Chlorogenic acid further slows down the speed of glucose entering the bloodstream after every meal since it is an inhibitor of glucose-6-phosphatase. It can control blood sugar and help in the maintenance of appropriate appetite with minimum cravings, especially for sugary foods.

3. Boosts Metabolism
Some studies have shown that chlorogenic acid can activate thermogenesis, the calorie-burning process the body undergoes to produce heat. The increase in energy expenditure is obtained through calories and contributes to weight loss in an individual.

4. Appetite Control
Chlorogenic acid can contribute to appetite control by raising satiety, which will in turn lower food intake and a person’s calorie consumption, leading to weight loss.

5. Decrease in BMI
For instance, a few clinical studies have found chlorogenic acid supplementation to result in a decrease in BMI and body fat percentage, but results vary, and more research is needed in order to confirm these effects consistently.

Applications of Chlorogenic Acid

Chlorogenic acid has a broad antibacterial effect, inhibiting various bacteria such as hemolytic streptococcus, dysentery rod gas, and salmonella typhi. It is used medicinally to treat upper respiratory tract infections and acts as an anti-inflammatory and antipyretic agent, helping to cool the blood and dissipate heat.

Additionally, chlorogenic acid enhances white blood cell production and shortens blood clotting and bleeding time. It is utilized in pharmaceutical raw materials and intermediates, and it effectively clears heat and removes toxicity.

In the food industry, chlorogenic acid is used as an additive in coffee products, chewing gum, and mint for added health benefits. It also possesses antiviral properties, providing protection against viral infections, and has hemostatic properties that help in stopping bleeding. Overall, chlorogenic acid contributes to general health improvement and offers several therapeutic benefits.

Reference:

  1. Khang Wei Ong et. al. Biochemical pharmacology, 85(9), undefined (2013-2-19)
  2. Margreet R Olthof et. al. The Journal of nutrition, 133(6), undefined (2003-5-29)
  3. Aimée E van Dijk et. al. Diabetes care, 32(6), undefined (2009-3-28)