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Sodium Hyaluronate VS Hyaluronic Acid

In terms of chemical structure, hyaluronic acid is an acidic mucopolysaccharide. Sodium hyaluronate is a type of salt of HA. Sodium content is more stable.

From the point of application, sodium hyaluronate is the sodium form of hyaluronic acid, and hyaluronic acid generally exists in the form of sodium salt in the application. Therefore, the basic cosmetics in the market are sodium hyaluronate.

Sodium hyaluronate, a skin conditioner, is an acidic mucopolysaccharide that naturally exists in the corneal skin and absorbs 1000 times its own weight of moisture in order to retain skin moisture, prevent moisture loss through the epidermis, and repair the barrier when the skin is damaged. It can improve skin nutrition metabolism, make skin soft, smooth, and wrinkle-free, increase elasticity, prevent aging, and moisturize at the same time, and is a good transdermal absorption enhancer. In combination with other nutrients, it can play a more desirable role in promoting nutrient absorption.

1. Sodium hyaluronate is a substance extracted from the cockscomb, also can be fermented by Lactococcus lactis, white or white particles or powder, the odorless, dry, nitrogen content of 2.8% – 4.0%, glucuronic acid content of 37.0% – 51.0%. It is used more in cosmetics and has a moisturizing effect.

2. Sodium hyaluronate itself is one of the components of human skin, is the most widely distributed acid mucosa in the body, exists in the matrix of connective tissue, and has a good moisturizing effect.

Sodium hyaluronate and phospholipid constitute an emulsifier

In the absence of other emulsifiers, the addition of HA and phospholipids in the oil-water mixture can form a stable emulsion. This emulsion is characterized by both emulsifying and water-retaining functions. It is a safe and effective emulsifier that other synthetic surfactants cannot be compared with. It can be used in skin creams and emulsions, the preparation of liquid, and cleansing milk.

Hyaluronic acid and polyoxyethylene thickener

Polyoxyethylene (molecular weight is 100-5000KD) is a commonly used thickener for cosmetics. The high molecular weight HA solution also has a high viscosity. The viscosity of the two solutions is much higher than the sum of their respective viscosity. Therefore, the combination of the two is a good thickener. At the same time, HIA has a good water-locking function and can be used to prepare various translucent viscoelastic yoke, Gels, such as shaving gel, eye gel, sunscreen gel, etc.

HA as flavoring fixative

According to the characteristics of molecular encapsulation of various substances by HA, it can be used in flavoring varieties. HA can be used as a fixative to combine with essence. It can reduce the volatilization rate of aroma and make the fragrance more durable. It is suitable for perfumes, skincare creams, emollients, air fresheners, deodorants, etc. HA has two advantages besides fixed fragrance. The first is to reduce the bad stimulation of essence to sensitive skin. The second is to organize some flavors and skin secretions to produce adverse chemical reactions, to prevent odor formation.

Conclusion:

Now, let’s summarize the differences in the HA vs. sodium hyaluronate challenge.

Hyaluronic acid and sodium hyaluronate are kind of similar yet different in their molecular size and functionality. Sodium hyaluronate is a salt form of HA, containing a much smaller molecule, hence its ability for deeper permeation into the skin. While both are used for hydration and tissue repair, sodium hyaluronate is more stable and can penetrate deeper layers of the skin, hence ideal for injectable fillers and deep hydration.