Sodium hyaluronate is a sodium salt of hyaluronic acid used extensively in skincare products. This derivative of hyaluronic acid is a group of sugar units composed of Na-glucoronate-N-acetyl glucosamine. It can be found in body tissues and fluids and decreases as we become old. So a large amount of cosmetic-grade sodium hyaluronate is produced for replenishment and water retention.

Cosmetic Grade Sodium Hyaluronate

Cosmetic-grade sodium hyaluronate offers lots of benefits to the human body and skin. Apart from the cosmetic grade, the food grade and the medical grade are highly hydrating and repairing as well. Here we are going to discuss sodium hyaluronate, its usage, and products in detail.

What Are the Skin Benefits of Cosmetic Grade Sodium Hyaluronate?

It is quite easy to find cosmetic-grade sodium hyaluronate content in serums, lotions, and other skincare products for its moisturizing and anti-aging effects. Your skin will be rejuvenated from the inside out thanks to the following benefits.

• Hydration: Sodium hyaluronate is extremely hydrating because it can attract and bind moisture from the environment to reduce dryness. In the long term, you are going to have smoother and plump skin.
• Prevention: Sodium hyaluronate could remove inflammatory factors and free radicals in your body to prevent redness, acne, black spots, wrinkles, and other damage to your skin.
• Repair: Doctors could use sodium hyaluronate content widely to heal wounds. So the salt is applied to the medical sectors for joint surgeries, dry eye syndromes, etc.

Sodium Hyaluronate VS Hyaluronic Acid

Both sodium hyaluronate and hyaluronic acid serve as humectants in skincare products, makeup products, and cleansing products. Yet sodium hyaluronate has a better hydrating impact for the following reasons.

• Sodium hyaluronate could penetrate the surface of the skin because of its lower molecular weight. So sodium hyaluronate could reach the deeper place, while hyaluronic acid could only work on the surface most of the time.
• Sodium hyaluronate is more stable since it is less prone to oxidation. So the derivative of HA offers better performance in skincare products.
• HA and its sodium salt are interchangeable in the cosmetic industry. Both of them are ideal choices for beauty lovers.

Related reading: Which Is Better, Hyaluronic Acid or Sodium Hyaluronate?

Cosmetic-Grade Sodium Hyaluronate Products to Use

Stanford Chemicals is a leading supplier of cosmetic-grade sodium hyaluronate and related products. There are sodium hyaluronates of high molecular weight, middle molecular weight, and low molecular weight on our website. Check the table below to find suitable products.

Table 1 Cosmetic Grade Sodium Hyaluronate Products

Is Sodium Hyaluronate FDA approved?

Sodium hyaluronate has been approved by the Food and Drug Administration (FDA) for use in the cosmetic industry as a dermal filler. Besides, the cosmetic grade hyaluronic acid of Stanford Chemicals is Ecocert certificated, and our daily operation is conducted according to ISO 9001 and GMP standards. You can check our website and find satisfied sodium hyaluronate products.

However, cosmetic-grade sodium hyaluronate is supposed to be used under safe dosage by licensed professionals. The table below shows sodium hyaluronate products approved by the FDA and their recommended dosage. [1]

Table 2 The Recommended Dosage of Sodium Hyaluronate

[1]

Conclusion

Sodium hyaluronate is a stable derivative of hyaluronic acid, and it is applied to various fields such as the cosmetic industry. Compared with hyaluronic acid, sodium hyaluronate has an enhanced skin-refreshing effect. Standard Chemicals provides cosmetic-grade sodium hyaluronate and other related products. For more information, please check our homepage.

Reference:

[1] Louisiana Department of Health. Sodium Hyaluronate. Louisiana Department of Health. chrome-extension://efaidnbmnnnibpcajpcglclefindmkaj/https://ldh.la.gov/assets/medicaid/MCPP/6.9.20/410_UHC-SodiumHyaluronate.pdf

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Sodium hyaluronate is the sodium salt of hyaluronic acid, a glycosaminoglycan found in the various connective tissue of humans. It occurs naturally in the human body and is central to regulating cell growth and renewal. In fact, it is found extensively in connective, epithelial, and neural cells. As such, hyaluronic acid has found its way into many skincare products, it can retain moisture, keep the skin firm, and prevent wrinkles by adding volume to the skin. It is also used to prevent the effects of aging. It is regarded as “the key to the fountain of youth.”

Sodium Hyaluronate aqueous solution of high viscosity will enable the water phase thickening; emulsified with the oil phase even after the fine paste, the role of a stable emulsion is to prevent cells produce a number of enzymes to reduce the formation of free radicals in the prevention of free radical damage to cell structure, resulting in lipid peroxidation and aging, such as the body has an important role.

Sodium Hyaluronate vs Hyaluronic Acid

The role of cosmetic grade sodium hyaluronate on the skin surface, molecules of hyaluronic acid can be formed on the surface of the skin layer of breathable film, the skin smooth and moist, and blocking external bacteria, dust, and UV intrusion, protecting the skin from infringement; small molecule transparent acid could infiltrate into the dermis, with a slight expansion of capillaries to increase blood circulation, improve intermediary metabolism, and promote the role of the skin to absorb nutrients, eliminate wrinkles with strong features, increase skin elasticity, slow down skin aging.

Hyaluronic acid can promote epidermal proliferation and differentiation of cells to remove oxygen-free radicals and can prevent and repair skin damage. The hyaluronic acid aqueous solution of high viscosity will enable the water phase thickening; emulsified with the oil phase even after the fine paste. The role of a stable emulsion is to prevent cells from producing a number of enzymes and to reduce the formation of free radicals in the prevention of free radical damage to cell structure, resulting in lipid peroxidation and aging, such as the body has an important role.

Sodium hyaluronate is used to treat skin ulcers such as bed sores or diabetic foot ulcers, as well as burn wounds, surgical incisions, cuts, abrasions, and other skin irritations.

Sodium hyaluronate topical is also used to treat dry or scaly skin.

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From the point of application, sodium hyaluronate is the sodium form of hyaluronic acid, and hyaluronic acid generally exists in the form of sodium salt in the application. Therefore, the basic cosmetics in the market are sodium hyaluronate.

Sodium hyaluronate, a skin conditioner, is an acidic mucopolysaccharide that naturally exists in the corneal skin and absorbs 1000 times its own weight of moisture in order to retain skin moisture, prevent moisture loss through the epidermis, and repair the barrier when the skin is damaged. It can improve skin nutrition metabolism, make skin soft, smooth, and wrinkle-free, increase elasticity, prevent aging, and moisturize at the same time, and is a good transdermal absorption enhancer. In combination with other nutrients, it can play a more desirable role in promoting nutrient absorption.

1. Sodium hyaluronate is a substance extracted from the cockscomb, also can be fermented by Lactococcus lactis, white or white particles or powder, the odorless, dry, nitrogen content of 2.8% – 4.0%, glucuronic acid content of 37.0% – 51.0%. It is used more in cosmetics and has a moisturizing effect.

2. Sodium hyaluronate itself is one of the components of human skin, is the most widely distributed acid mucosa in the body, exists in the matrix of connective tissue, and has a good moisturizing effect.

Sodium hyaluronate and phospholipid constitute an emulsifier

In the absence of other emulsifiers, the addition of HA and phospholipids in the oil-water mixture can form a stable emulsion. This emulsion is characterized by both emulsifying and water-retaining functions. It is a safe and effective emulsifier that other synthetic surfactants cannot be compared with. It can be used in skin creams and emulsions, the preparation of liquid, and cleansing milk.

Hyaluronic acid and polyoxyethylene thickener

Polyoxyethylene (molecular weight is 100-5000KD) is a commonly used thickener for cosmetics. The high molecular weight HA solution also has a high viscosity. The viscosity of the two solutions is much higher than the sum of their respective viscosity. Therefore, the combination of the two is a good thickener. At the same time, HIA has a good water-locking function and can be used to prepare various translucent viscoelastic yoke, Gels, such as shaving gel, eye gel, sunscreen gel, etc.

HA as flavoring fixative

According to the characteristics of molecular encapsulation of various substances by HA, it can be used in flavoring varieties. HA can be used as a fixative to combine with essence. It can reduce the volatilization rate of aroma and make the fragrance more durable. It is suitable for perfumes, skincare creams, emollients, air fresheners, deodorants, etc. HA has two advantages besides fixed fragrance. The first is to reduce the bad stimulation of essence to sensitive skin. The second is to organize some flavors and skin secretions to produce adverse chemical reactions, to prevent odor formation.

Conclusion:

Now, let’s summarize the differences in the HA vs. sodium hyaluronate challenge.

Hyaluronic acid and sodium hyaluronate are kind of similar yet different in their molecular size and functionality. Sodium hyaluronate is a salt form of HA, containing a much smaller molecule, hence its ability for deeper permeation into the skin. While both are used for hydration and tissue repair, sodium hyaluronate is more stable and can penetrate deeper layers of the skin, hence ideal for injectable fillers and deep hydration.

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