The topical delivery of large molecules through skin, hair, eyes, mucosal surfaces and bone is difficult using high molecular weight hyaluronic acid.

In the past, the most common form of hyaluronic acid is high molecular weight, usually, more than 1800 K Da.

The difference between regular, high-molecular hyaluronic acid (HA) and low-molecular-weight HA is that the low-molecular-weight HA has been split into smaller fragments.

Thereby, these smaller fragments can no longer form a gel with water like the large molecules, but they can penetrate the skin much easier and have actually a better anti-irritant and regenerating effect once absorbed by the skin.

super active hyaluronic acid

Now, after several years, our new product Micro-HA Super Active hyaluronic acid was used in Illustris molecule delivery technology to help facilitate a permeation process.

Micro HA is a kind of very low molecular weight HA (<5K Da). It is even lower than mini HA (<10K Da).

Micro Hyaluronic Acid helps plump skin to improve volume and suppleness. Due to its micro size, it penetrates deep into the skin to infuse moisture below the surface, providing skin replenishment and moisturization from the inside out.

Micro-HA Super Active Hyaluronic Acid is a new low molecular weight active ingredient produced by a unique enzymatic degradation technology with superb biological activity. Micro-HA can quickly penetrate the epidermis and the dermis to scavenge free radicals, reduce inflammation factor activity, repair damaged cells, and protect the skin against inflammation and sensitivity caused by various stimuli.

In the past, the traditional industry or traditional HA-related products are more suitable for adults. However, after several years, we have designed a brand new product of HA. It is named micro HA. Micro HA is a kind of very low molecular weight HA (<5K Da). It is even lower than mini HA (<10K Da). The main functions of Micro HA are recovery and super moisturizing the tissues. It can increase the protection of baby care from daily life.

One of the examples from our customers

One of our regular customers was focused on personal care products. In the past, they sell more products for adults, especially for women. However, after utilizing products Micro HA in their new products, they obtained a lot. It is not only can enrich their product sorts, but also expand the market sales for their company. Since the advanced specification of micro-HA, they can search the new products for baby care. Therefore, this is a win-win result, it is also good news for the HA market. We are both happy about this transaction.

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The polyanionic form, commonly referred to as hyaluronan, is a visco-elastic polymer found in the aqueous and vitreous humor of the eye and in the fluid of articulating joints.

Hyaluronic acid(HA) is a straight-chain macromolecular mucopolysaccharide composed of repeat disaccharide units of glucuronic acid and N-acetylglucosamine. It widely consists of the extracellular space of human and animal tissue, vitreum, umbilical cord, skin joints synovia, and cockscomb, etc.

Most cosmetic manufacturers make use of high molecular weight HA. This ingredient, when used at optimal levels of inclusion, is an incredibly effective moisture-binding element, providing superficial hydration of the epidermis for many hours. However, this ingredient is a macro-molecule and is too large to penetrate into the deeper layers of the skin.

Low molecular weight HA, on the other hand, has been engineered to exist as a far smaller molecule that is able to penetrate through the epidermis to provide deep hydration. It has been scientifically proven that increased levels of hyaluronic acid in the deeper layers of the skin actually stimulate the production of collagen fibers, which in turn will result in a firmer, more toned appearance.

HA is a new biological at home and abroad. Its molecular weight is from several ten thousand to several million. Its aqueous solution has outstanding moisture-keeping ability, high viscoelasticity, and lubricity. It is widely used in cosmetics, pharmacy and health, and beautiful food.

Biochemical drugs with high clinical value, are widely used in all kinds of eye surgery, such as crystal implantation, corneal transplantation, glaucoma surgery, etc.

It can also be used to treat arthritis and accelerate wound healing.

It is used in cosmetics, it can have a unique skin protection effect, can keep skin moist and smooth, delicate, soft, and elastic, has anti-wrinkle,  beauty care, and restore the skin physiology function.

1. Food supplements:

Hyaluronic Acid Powder through oral administration after digestion absorption, increases in vivo Hyaluronic Acid synthesis of the precursor, causing the skin and other organizations’ Hyaluronic Acid resultant quantity increases, thus enabling the skin the water retention property to increase, gaining rich elasticity, and reducing wrinkles.

2. Cosmetics applications:

Hyaluronic Acid Powder has an outstanding moisture-keeping ability, thus called the Natural Moisturizing Factor in the world. Hyaluronic Acid is a common ingredient in skin-care products, which can be used as a very effective topical humectant, which can be used for facial wrinkles, reduction of folds and wrinkles, and removal of scars.

3. Medical applications:

Hyaluronic Acid Powder could be used in eye surgery, such as corneal transplantation, cataract surgery, glaucoma surgery, and surgery to repair the retinal detachment.

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