Cosmetic Grade Hyaluronic Acid – Stanford Chemicals https://www.stanfordchem.com Global Supplier of Hyaluronic Acid & Chondroitin Sulfate Fri, 28 Mar 2025 07:56:51 +0000 en-US hourly 1 https://wordpress.org/?v=4.9.18 https://www.stanfordchem.com/wp-content/uploads/2018/08/cropped-STANFORD-CHEMICALS-LOGO-1-32x32.jpg Cosmetic Grade Hyaluronic Acid – Stanford Chemicals https://www.stanfordchem.com 32 32 Sodium Hyaluronate vs Ectoine: Which is Better for Skin and Eyes https://www.stanfordchem.com/sodium-hyaluronate-vs-ectoine-which-is-better-for-skin-and-eyes.html https://www.stanfordchem.com/sodium-hyaluronate-vs-ectoine-which-is-better-for-skin-and-eyes.html#respond Tue, 14 Jan 2025 10:27:07 +0000 https://www.stanfordchem.com/?p=10141 Understanding Sodium Hyaluronate and Ectoine As a key moisturizing ingredient, sodium hyaluronate is widely recognized. Let’s begin with a brief introduction. Sodium hyaluronate (the sodium salt form of hyaluronic acid) is a polysaccharide naturally present in human tissues. It is a transparent, viscous substance with excellent moisturizing, lubricating, and anti-inflammatory properties. It is a common […]

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Understanding Sodium Hyaluronate and Ectoine

As a key moisturizing ingredient, sodium hyaluronate is widely recognized. Let’s begin with a brief introduction.

Sodium hyaluronate (the sodium salt form of hyaluronic acid) is a polysaccharide naturally present in human tissues. It is a transparent, viscous substance with excellent moisturizing, lubricating, and anti-inflammatory properties. It is a common ingredient in skincare products and an effective component in eye drops for relieving dry eyes.

So, what is ectoine?

Ectoine is an amino acid derivative found in “Halophile” that thrives in extreme environments. In 1985, German scientist Professor Galinski discovered ectoine in the saline lakes of the Egyptian desert.

It regulates cell osmotic pressure, acting as a natural “protective shield” that enables halophilic bacteria to survive in extreme conditions like high temperatures, high salinity, and intense UV radiation. Biotech companies identified its potential and began producing ectoine (C₆H₁₀N₂O₂) through fermentation. Today, ectoine is used in biomedicine (eye drops, nasal sprays, oral sprays) and skincare products.

Sodium Hyaluronate vs Ectoine: Which is Better for Skin and Eyes

Fig 1. Desert salt lake with no grass growing

Sodium Hyaluronate vs Ectoine: Which is Better for Skin

Sodium hyaluronate has been used in skincare products since the 1980s. The exceptional moisturizing ability has made it a star ingredient in the skincare industry. Ectoine, widely adopted by skincare brands since 2019, has gained recognition for its outstanding moisturizing and repair effects, leading to rapid growth in its applications.

Let’s compare the effects of the two

1. Moisturizing

Both ingredients provide moisturizing benefits, but their mechanisms and results differ.

Sodium hyaluronate molecules can absorb hundreds to thousands of times their weight in water. It draws moisture from the environment and locks it in, keeping the skin hydrated. It also forms a breathable hydrating film on the skin’s surface, reducing water evaporation and preventing dryness. What’s more, low-molecular-weight HA can penetrate the dermis, offering deep hydration.

Sodium Hyaluronate benefits for skin

Fig 2. HA for skin

Ectoine’s moisturizing function differs, focusing more on protection and regulation. It binds with water molecules to form a stable hydration shell around cells, creating a protective shield. This shield effectively prevents water loss from skin cells and maintains water balance inside and outside the cells. Additionally, by stabilizing cell membranes and protein structures, ectoine enhances cellular resistance to external stressors like dryness, UV rays, and high temperatures, reducing water loss risks.

Sodium Hyaluronate vs Ectoine: Which is Better for Skin

Fig 3. The moisturizing principle of Ecdoin

Conclusion: Ectoine’s moisturizing ability leans toward “protective hydration,” without directly absorbing water like sodium hyaluronate. For those focused on hydration, sodium hyaluronate offers more immediate results.

2. Skin Repair:

Sodium hyaluronate is popular in skincare for its skin repair properties. It stabilizes and attracts growth factors (EGF), accelerating cell proliferation, tissue regeneration, and wound healing. It also has anti-inflammatory and soothing effects, reducing damage caused by inflammation.

Ectoine’s repair function is more prominent, especially for sensitive and inflamed skin. When exposed to environmental stressors like high temperatures, UV radiation, hypoxia, heavy metal toxicity, or viral infections, ectoine triggers emergency protective and regenerative responses, helping cells maintain normal physiological activity. Merck data shows that 1.0% Ecdoin can induce a faster stress response, prevent cell damage, and increase the speed of self-healing by 2-3 times.

Conclusion: For skin sensitivity, barrier damage, acne-related breakouts, or sunburn-induced redness, products with ectoine can quickly provide repair and soothing effects.

 

Key Characteristics Comparison:

Sodium Hyaluronate vs Ectoine: Which is Better for Skin

Sodium Hyaluronate vs Ectoine: Which is Better for Eyes

Sodium hyaluronate and ectoine are both vital ingredients in eye drops, but their benefits differ in focus.

Sodium hyaluronate is more suitable for individuals with dry eye syndrome, contact lens wearers, or those needing immediate hydration. Its properties allow it to absorb water and form a hydrating film on the eye surface, relieving dryness. Moreover, its natural presence in human tissues ensures high safety with minimal irritation.

Ectoine, on the other hand, is ideal for individuals with eye inflammation, sensitivity, or exposure to harsh environments. By forming a “hydration shell,” ectoine enhances the stability of ocular cells, protecting them from external irritants. It also stabilizes the lipid layer of the tear film, preventing excessive evaporation.

–Synergistic Effects of Sodium Hyaluronate and Ectoine

Studies show that combining ectoine with sodium hyaluronate delivers enhanced synergy in relieving dry eyes. This combination significantly improves water-binding ability, effectively hydrates the eyes, stabilizes the tear film, and reduces tear evaporation. Additionally, it forms a durable hydrating film on the eye surface, firmly adhering to the cornea and ocular surface to provide robust protection against external irritants. Furthermore, this combination is highly effective in alleviating irritation caused by environmental dryness, inflammation symptoms, and itching or burning sensations during allergic reactions.

 

Stanford Chemical Company (SCC) is an excellent supplier of sodium hyaluronate powder and ectoine powder. In addition, we also provide chondroitin sulfate for cataract surgery eye drops and joints. For more information on these materials, please check out our home page.

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Natural Ingredients vs. Chemical Ingredients in Skincare Products: Which Is Safer https://www.stanfordchem.com/natural-ingredients-vs-chemical-ingredients-in-skincare-products-which-is-safer.html https://www.stanfordchem.com/natural-ingredients-vs-chemical-ingredients-in-skincare-products-which-is-safer.html#respond Tue, 10 Dec 2024 08:35:25 +0000 https://www.stanfordchem.com/?p=10095 In today’s cosmetics market, consumers are paying more attention to the safety and efficacy of products. Discussions about natural ingredients have become increasingly popular in recent years. This trend has also influenced consumer behavior. According to statistics, more than 40% of shoppers prioritize natural ingredients in beauty and personal care products. Natural Ingredients in Skincare […]

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In today’s cosmetics market, consumers are paying more attention to the safety and efficacy of products. Discussions about natural ingredients have become increasingly popular in recent years. This trend has also influenced consumer behavior. According to statistics, more than 40% of shoppers prioritize natural ingredients in beauty and personal care products.

Natural Ingredients in Skincare Products

Generally, ingredients derived from natural resources and obtained through physical extraction or simple chemical processing are referred to as “natural ingredients.”

Natural Ingredients vs. Chemical Ingredients in Skincare Products: Which Is Safer

1. Herbal Extracts

Herbal extracts are common natural ingredients in cosmetics. For example, centella asiatica extract has repairing and anti-inflammatory effects. It is rich in triterpenoids, which promote collagen synthesis, speed up skin healing, and reduce inflammation, making it particularly beneficial for acne-prone and sensitive skin.

Chamomile extract is rich in flavonoids, which soothe the skin, reduce redness and itching, and provide antioxidant benefits, helping to relieve skin stress.

2. Natural Oils

Natural oils are moisturizing and nourishing ingredients in skincare products. For example, shea butter is rich in fatty acids and vitamins, which repair dry skin, enhance skin elasticity, and form a moisture-locking barrier on the skin surface.

Coconut oil has excellent penetrative properties, deeply moisturizing the skin. Its natural antibacterial properties help relieve inflammation, making it suitable for dry and sensitive skin.

3. Natural Polysaccharides and Proteins

Natural polysaccharides and proteins are important active ingredients in skincare products. For example, hyaluronic acid has exceptional hydrating properties. It can attract moisture and form a hydrating film on the skin surface, improving dryness and increasing elasticity.

Collagen is a natural protein that fills the gaps between skin cells, improving skin firmness and softness. Elastin is particularly effective in enhancing skin elasticity, suitable for anti-aging skincare needs.

4. Natural Acids

Natural acids are often used for exfoliation and brightening. For example, AHA (alpha-hydroxy acids), derived from fruit extracts, gently removes dead skin cells, improves dullness, and refines skin texture.

BHA (beta-hydroxy acids), derived from willow bark, penetrates pores to dissolve oil, reducing blackheads and acne. Lactic acid is known for its gentle exfoliation, making it suitable for sensitive skin.

5. Natural Minerals

Natural minerals are mainly used for sun protection and oil control. For example, titanium dioxide is a natural mineral sunscreen that reflects UV rays, protecting the skin from photoaging.

Kaolin clay is an absorbent mineral that effectively removes excess oil and impurities, purifies pores, and is often used in skin-cleansing products.

6. Other Natural Active Substances

Other natural active substances also play important roles in cosmetics. For instance, honey is a natural humectant rich in various sugars and minerals that deeply hydrate the skin and improve its barrier function.

Pearl powder is popular for its rich calcium and amino acid content, which not only whitens the skin but also reduces fine lines and dullness. Algae extracts contain a variety of minerals and polysaccharides, providing hydration, antioxidation, and enhanced skin repair. Spirulina, rich in proteins and vitamins, is one of the best ingredients for anti-aging skincare.

Natural Ingredients in Skincare Products

Chemical Ingredients in Skincare Products

Some ingredients, such as niacinamide (Vitamin B3), are naturally present in many foods, but extracting them directly from these sources is not economical. Their natural content is low, and the extraction cost is high, making it difficult to meet large-scale, high-purity demands. In such cases, synthetic production becomes a more reasonable choice.

Main Chemical Ingredients Overview

Type

Ingredient Benefits
Active Ingredients Niacinamide Whitening, antioxidant, evens skin tone
Retinol Anti-aging, promotes cell renewal
Ferulic Acid Enhances the stability of other antioxidants
Sodium Ascorbyl Phosphate Whitening, antioxidant
Glycolic Acid Exfoliation
Moisturizers Glycerin Hydration
Propylene Glycol Locks in moisture
Butylene Glycol Hydration, texture adjustment
PEG Compounds Hydration, emulsification
Urea Softens keratin, deep hydration
Preservatives Phenoxyethanol Broad-spectrum antibacterial, extends shelf life
Parabens Prevents bacterial and fungal growth
MIT High-efficiency preservative
Antioxidants Coenzyme Q10 Antioxidant, anti-aging
Benzophenone Absorbs UV rays
Ethyl Vitamin C Antioxidant
Texture Modifiers Silicones Smooths skin
Carbomer Thickening agent, forms gels
Polyacrylamide

Film-forming

 

Which Is Safer

Natural ingredients come from nature, retaining the diversity and potential synergistic effects found in their natural state. For example, chamomile extract offers both anti-inflammatory and soothing properties for the skin. In contrast, chemically synthesized ingredients lack these characteristics and primarily serve a single function.

However, despite the many advantages of natural ingredients in cosmetics, there are challenges and considerations to keep in mind. First, natural ingredients may be less stable than synthetic ones and can be easily affected by environmental factors such as temperature and light. Second, the extraction and processing of natural ingredients require strict controls to ensure their quality and safety. Additionally, even natural ingredients can sometimes cause allergic reactions, particularly for individuals with sensitive skin.

Of course, some chemical ingredients (such as high-concentration salicylic acid and paraben preservatives) can also cause irritation or even raise health concerns. Moreover, it is worth noting that certain chemical ingredients, such as silicones, may pose potential environmental risks.

Natural Ingredients vs. Chemical Ingredients in Skincare Products

Market Trends: Natural Ingredients Replacing Synthetic Ones

As health and environmental awareness grow, consumers are more inclined to choose cosmetics containing natural ingredients. This trend is driving companies to make changes.

Firstly, companies are focusing on selecting environmentally and socially friendly alternatives that do not compromise product efficacy, safety, or shelf life. Advances in green chemistry and biotechnology have provided solutions, such as replacing petroleum-derived emollients with plant-based oils or squalane from sustainable sources.

Replacing synthetic preservatives with natural ones is another significant shift. Plant extracts and essential oils, such as tea tree, cinnamon, and thyme extracts, are leading this change by offering effective antibacterial protection and enhancing the sensory properties of products.

 

Stanford Chemicals Company (SCC) has over 16 years of experience in the manufacture and sale of skin care and personal care ingredients. We offer skin care ingredient raw materials to meet a variety of skin care needs.

 

Reference:

Common Skin Care Ingredients You Need to Know

Acids in Skincare: What Are the Different Uses and Precautions

Hyaluronic Acid vs. Retinol vs. Vitamin C: Which Is Best for Skincare?

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Top 10 Benefits of Hyaluronic Acid https://www.stanfordchem.com/hyaluronic-acid-10-benefits.html https://www.stanfordchem.com/hyaluronic-acid-10-benefits.html#respond Tue, 09 Jul 2024 07:07:17 +0000 https://www.stanfordchem.com/?p=9715 Hyaluronic acid (HA), initially extracted from bovine vitreous humor, is a natural polysaccharide. It naturally exists in our bodies and is widely distributed in the eyes, joints, skin, umbilical cord, and other tissues. It plays many important roles in the human body. This article will explain in detail the top 10 benefits of HA on […]

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Hyaluronic acid (HA), initially extracted from bovine vitreous humor, is a natural polysaccharide. It naturally exists in our bodies and is widely distributed in the eyes, joints, skin, umbilical cord, and other tissues. It plays many important roles in the human body. This article will explain in detail the top 10 benefits of HA on the human body.

1. Hyaluronic Acid for Skin: Moisturizing and Anti-Aging

Hyaluronic acid is a component of the dermis layer of the skin, capable of retaining 100 times its weight in water. This is the source of its powerful moisturizing ability. Therefore, using HA can keep the skin hydrated, effectively improving dryness, roughness, and peeling.

For the skin, hyaluronic acid is not just a moisturizer; it also effectively combats aging. This is because HA can fill the gaps within the skin, smoothing out wrinkles and fine lines. Additionally, it increases skin elasticity, making the skin firmer and reducing sagging. As we age, supplementing with HA is a highly effective anti-aging strategy.

Read more:

Hyaluronic Acid Powder: The Acne-Prone Skin Savior

2. Hyaluronic Acid for Facial Contours: Filling Hollows and Smoothing Wrinkles

HA is a primary choice in cosmetic procedures for enhancing facial contours. Hyaluronic acid injections can fill in sunken areas of the face, such as the cheeks, temples, and chin, creating smoother and more defined facial lines. Additionally, it can smooth deep wrinkles, such as nasolabial folds and crow’s feet, lifting sagging facial skin and restoring a youthful, firm appearance.

Hyaluronic Acid for Facial Contours: Filling Hollows and Smoothing Wrinkles

Fig 1. Hyaluronic Acid for Facial Contours: Before and After

3. Hyaluronic Acid for Lips: Safe Lip Augmentation

Injectable-grade hyaluronic acid is a common method for lip augmentation. By injecting HA, the appearance of the lips can be significantly improved, making them fuller and more defined. Additionally, HA injections can effectively reduce fine lines and wrinkles on the lip surface.

Even without injections, applying HA directly to the lips has benefits. Because of its moisturizing properties, it helps the lips retain moisture, preventing dryness and cracking. Moreover, its anti-inflammatory properties can alleviate symptoms of lip inflammation, reducing redness and discomfort.

Hyaluronic Acid for Lips: Safe Lip Augmentation

Fig 2. Injectable-grade HA on Lips: Before and After

Read more:

Fuller Lips Made Easy: The Power of Hyaluronic Acid

4. Hyaluronic Acid for Wound: Promoting Healing and Reducing Scars

The strong moisturizing capability of hyaluronic acid is not only beneficial for the skin but also accelerates wound healing. It forms a protective film, locking in moisture and preventing the wound from drying and scabbing. Additionally, HA has anti-inflammatory properties, reducing inflammation at the wound site.

Another important role of HA in wound healing is promoting skin regeneration. It facilitates cell migration and proliferation, crucial steps in the healing process. Moreover, HA can reduce scar formation by promoting collagen synthesis, which enhances the strength and elasticity of new tissue, thus minimizing scarring.

Hyaluronic Acid for Wound: Promoting Healing and Reducing Scars

Fig 3. The three phases of wound healing

Read more:

Medical Grade Hyaluronic Acid and Wound Healing

5. Hyaluronic Acid for Eyes: Relieving Dryness and Protecting the Cornea

Hyaluronic acid can keep the surface of the eyeball moist, significantly relieving dryness, irritation, and discomfort. Thus, eye drops and gels containing HA are widely used to treat dry eye syndrome and other eye discomforts.

In addition to relieving dry eye symptoms, hyaluronic acid has numerous benefits in eye surgeries. It forms a protective film, preventing dust, bacteria, and other harmful substances from damaging the cornea. In cataract and other intraocular surgeries, hyaluronic acid serves as a filling material, helping maintain the stability of intraocular structures and protecting intraocular tissues. Furthermore, it can be used as a surgical aid, reducing intraoperative damage and promoting postoperative healing.

Read more:

Sodium Hyaluronate for Dry Eyes and How It May Increase Intraocular Pressure

6. Hyaluronic Acid for Joints: Relieving Pain and Delaying Degeneration

Hyaluronic acid has a significant effect on alleviating joint inflammation. It is a crucial component of synovial fluid, providing excellent lubrication. It reduces friction between joint surfaces, protecting cartilage and reducing pain and discomfort during joint movement.

By improving lubrication and reducing pain, HA can enhance joint flexibility and stability, reducing stiffness. Additionally, it protects and repairs joint cartilage, slowing its degeneration.

Anatomy of the healthy and osteoarthritic knee joint

Fig 4. Anatomy of the healthy and osteoarthritic knee joint[i]

Read more:

Hyaluronic Acid VS. Glucosamine VS. Chondroitin: Which Is Best for Joints?

7. Hyaluronic Acid for Bones: Preventing Osteoporosis

Hyaluronic acid is a key component of the bone matrix, playing an important role in bone health. It provides structural support to bones, promoting the formation and maintenance of the bone matrix.

In the healing process of fractures and bone injuries, HA also plays a crucial role. It promotes the proliferation and differentiation of osteoblasts, accelerating bone regeneration and repair, thus shortening the healing time. Moreover, its anti-inflammatory properties reduce inflammation after bone injuries.

Hyaluronic acid helps prevent osteoporosis by promoting the deposition of minerals (such as calcium and phosphorus) in bones, increasing bone density and strength.

8. Hyaluronic Acid for Hair: Preventing Dryness and Enhancing Strength

Hair that lacks moisture becomes dry and frizzy. Hyaluronic acid, with its moisturizing ability, helps hair retain moisture, making it softer and smoother. Similarly, it keeps the scalp hydrated, preventing dryness and flaking, and promoting a healthy environment for hair growth.

Moreover, HA enhances hair strength and elasticity, reducing breakage and split ends. Its antioxidant properties also benefit hair health by neutralizing free radicals and reducing oxidative stress damage, maintaining the health of the hair.

9. Hyaluronic Acid for Brain: Protecting Nerves

Hyaluronic acid plays a significant role in neuroprotection. It protects nerve cells from external damage, reducing apoptosis and injury. Additionally, hyaluronic acid is an important component of the brain’s extracellular matrix, providing structural support and maintaining the health of the extracellular matrix.

Researchers have noticed the potential of HA in improving cognitive function. By enhancing the health and function of nerve cells, HA may support learning and memory. Its anti-inflammatory and neuroprotective effects could also help reduce age-related cognitive decline.

Hyaluronic Acid for Brain: Protecting Nerves

Fig 5. Different forms of HA scaffolds[ii]

10. Hyaluronic Acid for Teeth: Protecting Gums

Hyaluronic acid significantly protects and repairs gum tissue. It can keep gum tissue hydrated and enhance the barrier function of the gums, preventing bacteria and toxins from invading. Additionally, HA has excellent anti-inflammatory effects. It can inhibit the release of inflammatory factors, alleviating gum inflammation and periodontal disease.

The ability of hyaluronic acid to promote wound healing plays a crucial role in accelerating the healing of oral injuries and post-surgical recovery. Therefore, after tooth extractions or implants, HA can speed up wound healing and reduce postoperative complications.

Conclusion

Hyaluronic acid’s multifaceted benefits span across various aspects of health and beauty, from maintaining skin hydration and enhancing facial contours to promoting joint and bone health. Its unique properties make it an invaluable component in medical treatments and cosmetic applications, improving overall quality of life. As research continues to uncover new potential uses, hyaluronic acid is set to remain a cornerstone of health and wellness.

 

Stanford Chemical Company (SCC) is an excellent supplier of Sodium Hyaluronate Powder. We provide cosmetic-grade, food-grade, medical-grade, and injection-grade sodium hyaluronate powder. For more information about these materials, please check out our home page.

[i] Fig 4. Anatomy of the healthy and osteoarthritic knee joint. Created via canvas. Source: Smith, Abbi & Sigurbjörnsdóttir. (2022). Hedgehog signaling in bone and osteoarthritis: the role of Smoothened and cholesterol. The FEBS Journal. 290. 10.1111/febs.16440.

[ii] Jensen, G.; Holloway, J.L.; Stabenfeldt, S.E. Hyaluronic Acid Biomaterials for Central Nervous System Regenerative Medicine. Cells 2020, 9, 2113. https://doi.org/10.3390/cells9092113

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Hyaluronic Acid vs. Retinol vs. Vitamin C: Which Is Best for Skincare? https://www.stanfordchem.com/hyaluronic-acid-vs-retinol-vs-vitamin-c.html https://www.stanfordchem.com/hyaluronic-acid-vs-retinol-vs-vitamin-c.html#respond Wed, 05 Jun 2024 08:22:04 +0000 https://www.stanfordchem.com/?p=9654 For skin care, many products promise amazing effects. Hyaluronic acid, retinol and vitamin C are among the most commonly mentioned. So, which of these products is best for skin? Before we compare, let’s take a closer look at these three different products. Hyaluronic Acid Hyaluronic acid (HA) is a polysaccharide found in human tissues, especially […]

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For skin care, many products promise amazing effects. Hyaluronic acid, retinol and vitamin C are among the most commonly mentioned. So, which of these products is best for skin? Before we compare, let’s take a closer look at these three different products.

Hyaluronic Acid

Hyaluronic acid (HA) is a polysaccharide found in human tissues, especially skin, joints, and eyes. And it is renowned for its exceptional moisturizing ability. HA can absorb and retain up to 1000 times its weight in water. This ability makes it a widely used ingredient in skin care products.

–How HA Benefits the Skin?

Hyaluronic acid has strong moisture absorbing properties, leaving the skin with a deep gloss and gentle elasticity. It can act as a protective layer for the skin, preventing moisture loss and providing balanced skin moisture.

As we age, the amount of hyaluronic acid in our skin decreases, leading to dullness, loss of elasticity and fine lines. Hyaluronic acid supplements can increase skin hydration and elasticity, and reduces fine lines and wrinkles, giving skin a more youthful appearance.

Hyaluronic acid also has excellent repairing and soothing properties. It supports skin cell regeneration and repair, helps damaged skin heal, relieves skin pain caused by dryness or irritation, and reduces inflammation and redness.

Retinol

Retinol is a derivative of vitamin A, widely used in skincare products for its remarkable anti-aging and skin texture-improving abilities.

–How Retinol Works?

Retinol penetrates the dermis and promotes cell renewal. It accelerates the shedding of old dead skin cells and promotes the growth of new healthy cells. This process not only smooths and evens out skin texture, but also helps prevent clogged pores and reduce acne.

Retinol stimulates collagen production. It helps us improve skin elasticity and firmness, and reduce fine lines and wrinkles. In addition, it accelerates the shedding of the stratum corneum (the outermost layer of the skin), revealing fresher and smoother skin underneath.

It also regulates sebaceous gland activity, reduces excess oil secretion, reduces shine, and makes the skin more refreshed. In addition, retinol helps to fade pigmentation, even out skin tone, and solve problems such as sun spots and age spots.

Vitamin C

Vitamin C is a powerful antioxidant widely used in skincare products for its brightening and anti-aging effects.

–How Does Vitamin C Benefit the skin?

Vitamin C effectively inhibits melanin production. This helps to lighten dark spots and hyperpigmentation. The result is a brighter complexion, more even-toned, and radiant skin.

One of the powerful effects of vitamin C is that it neutralizes free radicals. Free radicals are unstable molecules that cause premature aging, wrinkles, and dull skin. This powerful antioxidant also protects the skin from environmental damage, including harmful UV radiation.

In addition, vitamin C plays a vital role in collagen synthesis, which is essential for enhancing skin elasticity and firmness. By boosting collagen production, it helps maintain a youthful and supple appearance of skin, reducing signs of aging and improving overall skin health.

In Conclusion: Combination Is Best

Deciding which is better between hyaluronic acid, retinol, and vitamin C depends on individual skin needs and goals. For intense hydration, hyaluronic acid is unmatched. For anti-aging and wrinkle reduction, retinol is the go-to. For brightening and protection against environmental damage, vitamin C is ideal.

Often, the best results come from a balanced combination of these ingredients, tailored to your specific skincare concerns and routine. Given their different focus areas, can hyaluronic acid, retinol, and vitamin C be used together for skincare?

The answer is that they can be used in combination.

Hyaluronic Acid vs. Retinol vs. Vitamin C: Which Is Best for Skincare?

Fig 1. Structures of Hyaluronic Acid, Retinol and Vitamin C

–Hyaluronic Acid with Retinol

Retinol can sometimes cause dryness or irritation, especially when first used. This is where hyaluronic acid comes in. Its moisturizing properties can help alleviate the dryness or sensitivity caused by retinol, making the skin more tolerant. Additionally, hyaluronic acid works on the skin’s surface to provide immediate hydration, while retinol penetrates deeper into the skin to address fine lines, wrinkles, and collagen production. Together, they tackle multiple signs of aging, making the skin smoother and younger-looking.

–Hyaluronic Acid with Vitamin C

The primary benefit of using vitamin C and hyaluronic acid together is their ability to brighten the complexion and improve overall skin tone. Vitamin C helps fade dark spots and pigmentation, making the skin tone more even. Hyaluronic acid hydrates the skin, plumping it up and reducing the appearance of fine lines and wrinkles. Another benefit of this powerful combination is that it can prevent environmental damage. Vitamin C acts as a barrier, neutralizing free radicals and preventing them from damaging the skin. On the other hand, hyaluronic acid forms a barrier on the skin’s surface, locking in moisture and preventing pollutants and toxins from penetrating the skin.

–Retinol with Vitamin C

Vitamin C inhibits melanin production, fading dark spots and pigmentation, making the skin more even-toned and radiant. Retinol promotes the shedding of the stratum corneum, helping to remove aging keratinocytes and making the skin smoother and brighter. Retinol promotes collagen production and cell turnover, reducing fine lines and wrinkles, while vitamin C, through its antioxidant action and collagen synthesis promotion, further enhances skin elasticity and firmness. Using both together can more effectively combat aging.

However, while vitamin C and retinol can be used together, it is best to use them at different times. Use vitamin C in the morning with sunscreen and retinol in the evening. Applying retinol after waiting 10-30 minutes following vitamin C application can help avoid potential irritation.

 

Stanford Advanced Materials (SCC) is at the forefront of developing hyaluronic acid and herbal extracts. Providing cosmetic-grade HA, Vitamin A, B, C, D, E and other extracts. For more information on these products or specific applications, please feel free to contact us to view our homepage.

 

Related Articles:

The Role of Vitamins and Hyaluronic Acid in Eye Health

What’s More Effective for Wrinkles: Hyaluronic Acid or Retinol?

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Acne Scars Vanish With Hyaluronic Acid https://www.stanfordchem.com/acne-scars-vanish-with-hyaluronic-acid.html https://www.stanfordchem.com/acne-scars-vanish-with-hyaluronic-acid.html#respond Mon, 11 Nov 2019 06:41:17 +0000 https://www.stanfordchem.com/?p=7360 Acne scars and other wound marks are challenging cosmetic problems to deal with. Almost everyone experiences acne and those scary-looking scars during their teenage years. However, this does not mean that you have to put up with it. Thanks to medical science, there are many safe and effective treatments available to remove and prevent further […]

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Acne scars and other wound marks are challenging cosmetic problems to deal with. Almost everyone experiences acne and those scary-looking scars during their teenage years. However, this does not mean that you have to put up with it. Thanks to medical science, there are many safe and effective treatments available to remove and prevent further scars. Hyaluronic acid is one of the well-researched and applied methods which can surely remove all those ugly marks on your skin within a few weeks.

Our skin’s health is directly linked to the interaction of skin cells, called fibroblasts, and collagen. Along with the age and exposure to ultraviolet rays, this connection between collagen and fibroblasts weakens resulting in poor skin health. Here hyaluronic acid helps in reviving the growth of collagen. This plumps your skin and removes all the pits and scars.

hyaluronic acid for skin

Also, hyaluronic acid being a natural skin moisturizer removes the dryness and roughness caused due to injuries. The improvements due to this treatment become clearly visible within a month or a few weeks. Normally, you do not need a repeated dose before 6 months.

As cosmetic-grade hyaluronic acid is such an important cosmetic product, almost all cosmetic companies are using it. This, of course, leads to variation in quality. Talking specifically about treating acne scars, low viscosity HA with a bit higher concentration is known to work well. You may also use pills and ointments, but it is best to consult a dermatologist.

Side effects are a major concern for almost everyone who is new to this method. Till now, hyaluronic acid is not known to cause anything more serious than swelling or temporary bleeding. So, it can be considered a safe and effective method to get rid of your acne scars.

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Hyaluronic Acid – Content, Location and Functions in Human Body https://www.stanfordchem.com/hyaluronic-acid-content-location-and-functions-in-human-body.html https://www.stanfordchem.com/hyaluronic-acid-content-location-and-functions-in-human-body.html#comments Mon, 28 Oct 2019 06:02:40 +0000 https://www.stanfordchem.com/?p=7344 Hyaluronic Acid (HA) is found in almost every cell in the human body and occurs in the highest concentrations in several specific body locations. The average Hyaluronic Acid in our bodies is estimated to be around 15 grams. It is distributed in almost every part of the body and has multiple functions. It is a […]

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Hyaluronic Acid (HA) is found in almost every cell in the human body and occurs in the highest concentrations in several specific body locations. The average Hyaluronic Acid in our bodies is estimated to be around 15 grams. It is distributed in almost every part of the body and has multiple functions. It is a well-proven fact that HA improves skin hydration, and elasticity while stimulating skin collagen production. In addition, it performs antioxidant and free radical protection, as well as cushioning joints and nerve tissues. It has also been confirmed that it possesses antibacterial and anti-inflammatory characteristics.

Nearly 50 % of the body’s HA is located in the collagen of skin and lips. Cosmetic-grade hyaluronic acid is an excellent skin moisturizer and its properties and functions contribute to increased smoothness and reduced wrinkling. It is also present in the joints – it acts as a shock absorber lubricating the fluid in the joint tissues.

hyaluronic acid content

HA is also claimed to remove or neutralize metabolic waste products resulting from the destruction of the cartilage, thus bringing relief from severe joint pain. This really omnipresent compound is a vitally important component of the human eye located in the vitreous fluid, where its content is reaching almost 80%. Beneficial effects have been reported of the supplementation with this substance on eye tissues, especially for people suffering from dry eyes. Medical grade hyaluronic acid is a substantial connective tissue component in the gums playing important roles in the regeneration of the gum tissue and reducing any inflammation that leads to bleeding gums. Recent research shows that the throat and other mucous membranes have large concentrations of HA.

Hyaluronic Acid is widely present in the connective tissue (tendons, ligaments, etc.) found everywhere in the body. Its major functions here are binding, support, protection, and insulation. It is located as well in the scalp and hair follicles, nourishing and hydrating the tissue which gives rise to hair.

Is it not incredible that the high presence of hyaluronic acid is found even in the fetal tissues! There it forms a very special substance in which embryonic cells have the perfect environment to develop and multiply rapidly. Could one light-heartedly say it is not essential to life?

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How Can Hyaluronic Acid Combat Aging? https://www.stanfordchem.com/how-can-hyaluronic-acid-combat-aging.html https://www.stanfordchem.com/how-can-hyaluronic-acid-combat-aging.html#comments Mon, 21 Oct 2019 10:05:16 +0000 https://www.stanfordchem.com/?p=7339 Aging is a natural process that affects various aspects of our skin, leading to signs such as wrinkles, dryness, and loss of elasticity. Among the many skincare ingredients available, hyaluronic acid has gained significant attention for its remarkable ability to combat these aging signs. But how exactly does hyaluronic acid work to keep our skin […]

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Aging is a natural process that affects various aspects of our skin, leading to signs such as wrinkles, dryness, and loss of elasticity. Among the many skincare ingredients available, hyaluronic acid has gained significant attention for its remarkable ability to combat these aging signs. But how exactly does hyaluronic acid work to keep our skin looking youthful? Let’s delve into its mechanisms and benefits.

What is Hyaluronic Acid?

Hyaluronic acid (HA) is a naturally occurring substance in our bodies, primarily found in the skin, eyes, and connective tissues. Its main function is to retain moisture, keeping tissues well-lubricated and hydrated. With age, the natural levels of hyaluronic acid in the skin decline, contributing to dryness and the formation of wrinkles.

hyaluronic acid for aging

Moisture Retention and Hydration

One of the primary ways hyaluronic acid combats aging is through its exceptional ability to retain moisture. HA can hold up to 1,000 times its weight in water, creating a plump, hydrated appearance in the skin. This deep hydration helps to smooth out fine lines and wrinkles, making the skin look firmer and more supple.

Enhancing Skin Elasticity

As we age, the skin’s elasticity decreases, leading to sagging and the formation of wrinkles. Hyaluronic acid helps to improve skin elasticity by promoting the production of collagen and elastin—proteins that are essential for maintaining the skin’s structure and resilience. Increased collagen production also aids in repairing damaged skin cells, further enhancing skin firmness.

Anti-Inflammatory Properties

Inflammation can accelerate the aging process by breaking down collagen and elastin fibers. Hyaluronic acid possesses anti-inflammatory properties that help soothe irritated skin and reduce redness. By minimizing inflammation, HA protects the skin from environmental stressors that contribute to premature aging.

Promoting Skin Repair and Regeneration

Hyaluronic acid plays a crucial role in the skin’s repair mechanisms. It facilitates the migration of skin cells to areas of damage, promoting faster healing and regeneration. This not only helps in reducing the appearance of existing wrinkles but also prevents the formation of new ones by maintaining healthy skin cell turnover.

Improved Skin Barrier Function

A strong skin barrier is essential for protecting against external aggressors such as pollutants and UV rays, which can cause oxidative stress and accelerate aging. Hyaluronic acid strengthens the skin barrier by enhancing its hydration levels, making it more resilient and less prone to damage.

Versatile Application in Skincare

Hyaluronic acid is a versatile ingredient that can be incorporated into various skincare products, including serums, moisturizers, and even injectable treatments like dermal fillers. Topical applications provide surface hydration and elasticity, while injectable HA can offer more profound, volumizing effects by replenishing lost volume in deeper skin layers.

Conclusion

Hyaluronic acid is a powerful ally in the fight against aging, thanks to its unparalleled ability to retain moisture, enhance skin elasticity, reduce inflammation, and promote skin repair. Incorporating HA into your skincare routine can help maintain a youthful, radiant complexion and mitigate the visible signs of aging. Whether through topical products or professional treatments, hyaluronic acid offers a multifaceted approach to achieving and sustaining healthy, vibrant skin.

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Something You Need To Know About Cosmetic Grade Hyaluronic Acid https://www.stanfordchem.com/something-you-need-to-know-about-cosmetic-grade-hyaluronic-acid.html https://www.stanfordchem.com/something-you-need-to-know-about-cosmetic-grade-hyaluronic-acid.html#respond Tue, 30 Apr 2019 07:17:57 +0000 https://www.stanfordchem.com/?p=6944 In recent years, the skincare industry has undergone tremendous changes. Today, let’s talk about hyaluronic acid. Let’s start with the basics. In the cosmetic industry, formulators are striving to get safer and more efficient cosmetic raw materials. Sodium Hyaluronate (HA), which is well-known as a natural moisturizing factor, is just this kind of compound. Stanford […]

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In recent years, the skincare industry has undergone tremendous changes.

Today, let’s talk about hyaluronic acid. Let’s start with the basics.

In the cosmetic industry, formulators are striving to get safer and more efficient cosmetic raw materials. Sodium Hyaluronate (HA), which is well-known as a natural moisturizing factor, is just this kind of compound.

hyaluronic acid for skin

cosmetic grade sodium hyaluronate

Stanford Chemicals as a professional HA manufacturer is managed strictly in accordance with GMP and ISO 9001 quality management systems to ensure the reliability and stability of products.

Hyaluronic Acid Advantages

1. High safety
2. ECOCERT certification
3. Non-animal origin bacterial fermentation
4. A series of safety tests carried out by authorized testing organizations
5. High purity

Cosmetic hyaluronic acid has very low impurities (such as protein, nucleic acid, and heavy metal).
There is no pollution of other unknown impurities and pathogenic microorganisms in the production process assured by strict production management and advanced equipment.

Main Cosmetic Grade Hyaluronic Acid and Its Functions

–High Molecular Weight Hyaluronic Acid

>1,000 kDa
Lubricating and film-forming, moisturizing, preventing skin damage, thickening, and keeping emulsion stable

–Low Molecular Weight Hyaluronic Acid

10 kDa~ 1,000 kDa
Nourishing the skin, long-lasting moisturizing

–Oligo Hyaluronic Acid

<10 kDa
Trans-dermal absorption, deep hydrating, anti-aging, repairing skin damage

Sodium Hyaluronate Crosspolymer(Hyaluronic Acid Elastomer)

Smooth and not sticky feeling; Forms a crosslinked network on the skin surface; Long-lasting moisturizing effect because of its good stability; Increases skin elasticity and reduces skin roughness.

–Substantive Sodium Hyaluronate

High substantivity, can be used in rinse-off products. As a conditioning moisturizer, it helps reduce the inflammation of the skin caused by surfactants present in formulas and feels smooth.

Hyaluronic Acid Applications

–Skincare

It is widely used in cream, emulsion, essence, lotion, gel, facial mask, etc. Hyaluronic acid (HA) acts on skin conditioning, which can automatically regulate different environments, keep the skin moist and refreshing, make the skin more elastic, and play the role of anti-wrinkle, anti-aging, and beauty.

The dosage of Hyaluronic Acid powder for skin care products is:
0.1% ~ 0.5% for HA powder
10% ~ 50% for HA solution
1-5% for Hyacross
0.5-1% for cation
Dissolving in water. Heating can accelerate the dissolution of HA.

–Makeup

Lipstick, eye shadow, foundation, etc.
Hyaluronic acid should be used as the first step in your beauty routine. It will create a protective barrier for your skin, keeping it moisturized and creating a better canvas for makeup and other beauty products.

–Cleansing

Facial cleanser, body wash, etc.
The first step to any skin treatment is cleansing. Using a good cleanser eliminates the dirt, sebum, and bacteria from the pores without drying your skin. On a wet face, gently massage the cleanser using circular motions in an upward and outward direction. Wipe it off with cotton wool and wash it off with warm water. Use a clay-cleansing mask once a week, if you have extremely oily skin.

–Haircare

Shampoo, hair conditioner, styling gel, hair restorer, etc.

Shampoo and conditioner use Hyaluronic Acid, formulated with amino acids and biotin isolates to visibly improve hair density, fullness, and softness. They are paraben and sulfate-free, using natural and innovative formulations to bring next-level haircare that is gentle enough for regular use.

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