Sodium Hyaluronate – Stanford Chemicals https://www.stanfordchem.com Global Supplier of Hyaluronic Acid & Chondroitin Sulfate Thu, 07 Nov 2024 09:30:36 +0000 en-US hourly 1 https://wordpress.org/?v=4.9.18 https://www.stanfordchem.com/wp-content/uploads/2018/08/cropped-STANFORD-CHEMICALS-LOGO-1-32x32.jpg Sodium Hyaluronate – Stanford Chemicals https://www.stanfordchem.com 32 32 HA4772 Pure Medical-Grade HA Powder (HA-EM3.0-SC) https://www.stanfordchem.com/medical-grade-sodium-hyaluronate.html Wed, 20 Dec 2023 07:40:06 +0000 https://www.stanfordchem.com/?post_type=product&p=9433 Stanford Chemicals Company (SCC) offers Pure Medical-Grade HA Powder  (HA-EM3.0-SC) for medical applications. Molecular Weight: 1,800K-2,500KDa. Intrinsic Viscosity: 2.72-3.53 m3/kg. CAS Number: 9067-32-7. Samples are available.

 

Related Products: Food Grade Sodium Hyaluronate, Cosmetic Grade Sodium HyaluronateInjection Grade Sodium HyaluronateCross-linked HA Gel Hyaluronic Acid​

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Pure Medical-Grade HA Powder (HA-EM3.0-SC) Introduction

HA-EM2.0-SC, a Medical-Grade Hyaluronic Acid Powder, boasts a molecular weight range of 1,800K to 2,500KDa and an intrinsic viscosity of 2.72 to 3.53 m³/kg. Specifically tailored for Eyedrop applications, this Hyaluronic Acid variant signifies a breakthrough in ocular care with optimal efficacy and safety in eye care formulations.

Pure Medical-Grade HA Powder (HA-EM3.0-SC) Features

Stanford Chemicals Company (SCC), a prominent wholesaler of organic hyaluronic acid, offers a comprehensive range of pure hyaluronic acid powders in high, medium, and low molecular weights. Our natural sodium hyaluronate powder is derived from non-animal sources, suitable for vegans, and meets kosher standards. Known for its exceptional moisture-retaining and viscoelastic properties, our products are widely used in the USA, Canada, and Europe across industries including food supplements, cosmetics, eye drops, and pharmaceuticals.

SCC excels in providing customized Vegan Medical-Grade Hyaluronic Acid Powder, such as HA-EMC-SC, which features customizable molecular weights. These specialized variants offer high adaptability and precise control over molecular properties, making them highly desirable solutions.

Our HA-EMC-SC stands out as a Pure Cosmetic-Grade Hyaluronic Acid Powder with customizable molecular weights, perfectly tailored to meet the specific requirements of various cosmetic formulations.

Pure Medical-Grade HA Powder (HA-EM3.0-SC) Functions

Medical Grade Hyaluronic Acid serves multifaceted functions in eye care.

  • It acts as a lubricant, providing a soothing and hydrating effect to alleviate dryness and discomfort in the eyes.
  • Its viscoelastic properties contribute to prolonged moisture retention on the ocular surface, aiding in maintaining optimal hydration levels for enhanced comfort.
  • Additionally, this specialized form of Hyaluronic Acid facilitates the protection of delicate eye tissues, forming a protective barrier against environmental irritants while supporting the natural healing process.

Pure Medical-Grade HA Powder (HA-EM3.0-SC) Specification

Items Specifications
Appearance White powder
Infrared absorption spectrophotometry Ph. Eur. Reference Standards
Appearance of solution A600nm≤0.01
pH (5mg/mL solution) 5.0-8.0
Intrinsic viscosity Measured values
Molecular weight 1800K-2500KDa
Sulfated glycosaminoglycans ≤1%
Nucleic acid A260nm≤0.5
Protein ≤0.1%
Chlorides ≤0.5%
Iron ≤80ppm
Heavy metals ≤20ppm
Loss on drying ≤20.0%
Bacterial counts ≤100cfu/g
Mold and Yeast ≤100cfu/g
Sodium hyaluronate 95%-105%
Glucuronic acid ≥42.0%

SDS of Medical Grade HA:

Pure Medical-Grade HA Powder Products

Main Product Item No. Specification
Medical Grade

Hyaluronic Acid

HA-EM2.0-SC M.W: 800K-1,300K Da,

I.V.: 1.44-2.12 m3/kg

HA-EM2.4-SC M.W: 1,300K-1,800K Da;

I.V: 2.12-2.72 m3/kg

HA-EM3.0-SC M.W:1,800K-2,500K Da;

I.V.: 2.72-3.53 m3/kg

HA-EMC-SC Customized Molecular weight

Pure Medical-Grade HA Powder (HA-EM3.0-SC) Applications

Only for parenteral preparations or oral preparations. Intra-articular and intra-ocular preparations are not included.

It can be used in eye drops, contact lens solutions, topical preparations for wound or burn healing, medical lubricants, etc. Medical-grade hyaluronic acid is rigorously purified and formulated for clinical use, ensuring safety and efficacy in various medical applications, including ophthalmology, orthopedics, and dermatology.

Medical Devices:

  • ophthalmic surgery (viscosupplementation)
  •  eye drops for dry eye (eg. artificial tears)
  • intra-articular injections
  • topical preparations for wound and burn healing
  • intradermal injections for aesthetic correction
  • anti-adhesive and shape-keeping products for thoracic and abdominal surgery
  • anti-adhesive wound healing products
  • bandages with exudates absorbing capacity.

Remedies /Drugs

Sodium hyaluronate on its own an active substance

  • cartilage (joint) and tendon disorders
  • wound and burn healing preparations

Sodium hyaluronate in combination with other active substances

  • anti-cancer preparations
  • wounds and burns healing preparations
  • preparations for reduction of scar formation
  • eye drops
  • topical anti-inflammatory and analgesic preparations
  • cartilage (joint) and tendon disorders
  • nutraceuticals supporting the treatment  of the skeleton or prevention of skeleton disorders
  • preparations for liver regeneration

Issue Engineering

  • artificial skin grafts for plastic and reconstruction surgery
  •  artificial skin for the test of cosmetic raw material
  • replacement of injured cartilage, artificial cartilage grafts
  • artificial bone grafts
  • adipose tissue replacement
  • support for the growth of soft tissue grafts
  • aorta and large venous grafts industry

Biotechnology and Molecular Biology

  • component of special cell culture medium
  • supporting material for gene transfer
  • biotinylated for the detection of hyaluronan-binding proteins

Other Biological Applications

  • sperm separation according to their mobility
  • medium for in vitro ovum fertilization. Only for parenteral preparations or oral preparations. Intra-articular and intra-ocular preparations are not included. It can be used in eye drops, contact lens solutions, topical preparations for wounds or burns healing, medical lubricants, etc.

SDS of Medical Grade HA:

Pure Medical-Grade HA Powder Products

 

Related Articles:

Hyaluronic Acid VS. Glucosamine VS. Chondroitin: Which Is Best for Joints?

What Are the Benefits of Hyaluronic Acid for Horse Health

Medical Grade Hyaluronic Acid and Wound Healing

Hyaluronic Acid: The Ultimate Moisturizer for Dry Eyes

Related Video:

How Does Sodium Hyaluronate Work?

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HA4761 Pure Cosmetic-Grade Hyaluronic Acid Powder (HAC-H-SC) https://www.stanfordchem.com/cosmetic-grade-sodium-hyaluronate.html Thu, 10 Jan 2019 05:31:11 +0000 https://www.stanfordchem.com/?post_type=product&p=6667 Stanford Chemicals Company (SCC) offers Cosmetic-Grade High Molecular Weight Hyaluronic Acid for skin care applications. High Molecular Weight > 1,800 kDa. CAS Number: 9067-32-7. Samples are available.

 

Related Products: Food Grade Sodium Hyaluronate, Medical Grade Sodium HyaluronateInjection Grade Sodium HyaluronateCross-linked HA Gel Hyaluronic Acid​

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Pure Cosmetic-Grade Hyaluronic Acid Powder (HAC-H-SC) Introduction

Hyaluronan as a function of raw material is widely used in cosmetics in the following aspects:

  1. Moisturizing and film-forming properties
  2. Anti-Wrinkles
  3. Anti-Irritation
  4. Nutrition delivery
  5. Free radical scavenging

Pure Cosmetic-Grade Hyaluronic Acid Powder Products

Main Product Item No. Specification
Cosmetic Grade

Hyaluronic Acid

HAC-Micro-SC M.W: <5 K Da

Ultra Low Molecular Weight

HAC-Oligo-SC M.W: 5-10 K Da

Low Molecular Weight

HAC-N-SC M.W: 200-600 K Da
HAC-L-SC M.W: 100-1,000 K Da(800 KDa)
HAC-M-SC M.W: 800-1,600 K Da

Middle Molecular Weight

HAC-H-SC M.W: >1,800 K Da

High Molecular Weight

HAC-C-SC Customized Molecular weight

 

SDS of Cosmetic Grade HA:

 

Pure Cosmetic-Grade Hyaluronic Acid Powder (HAC-H-SC) Features

  1. Reliable and safe:

Stanford Chemicals Company (SCC), a prominent organic hyaluronic acid wholesaler based in the USA, proudly presents its Ecocert-certified Cosmetics Grade Hyaluronic Acid. Our production adheres strictly to ISO 9001 and GMP standards, ensuring the highest quality.

Derived solely from fermentation, our pure hyaluronic acid is non-animal sourced, non-GMO, and free from any BSE/TSE risks. Within our comprehensive range, you’ll find high, middle, and low molecular weight natural hyaluronic acid powder, all meeting vegan standards and adhering to kosher guidelines. Notably, our HAC-C-SC stands out as a Cosmetic-Grade Hyaluronic Acid Powder, customizable in molecular weight to suit specific cosmetic formulations.

  1. High-purity and lower impurities: higher glucuronic acid content, lower protein, heavy metals, and nucleic acid content, compared with other cosmetics grade hyaluronic acid in the market.
  2. Different molecular weight ranges to meet different customers’ needs.

Pure Cosmetic-Grade Hyaluronic Acid Powder (HAC-H-SC) Functions

  • Nourishing the skin, long-lasting moisturizing;
  • Lubricating and film-forming, moisturizing, preventing skin damage, thickening and keeping emulsion stable;
  • Trans-dermal absorption, deep hydrating, anti-aging, repairing skin damage.
  • HMW-HA primarily sits on the skin’s surface, forming a hydrating and protective barrier. It helps retain moisture, plumps up the skin, and reduces the appearance of fine lines and wrinkles.
  • Often used in moisturizers, creams, and serums for hydration and anti-aging purposes.

HMW-HA vs MMW-HA vs LMW-HA: Differences between skin care applications

High Molecular Weight Hyaluronic Acid (HMW-HA) is ideal for use in moisturizers, masks, and protective creams, where surface hydration and barrier protection are critical. It is often included in formulations aimed at providing long-lasting moisture and reducing transepidermal water loss.

Medium Molecular Weight Hyaluronic Acid (MMW-HA)helps improve the repair of damaged tissues by stimulating the formation of the extracellular matrix, which enhances the skin barrier function. Additionally, it can reduce inflammatory responses, further supporting wound healing and cellular regeneration.

Low Molecular Weight Hyaluronic Acid (LMW-HA) is best suited for serums, essences, and deep-penetrating treatments. These formulations are designed to deliver hydration deep into the skin layers and promote cellular repair and regeneration.

HMW-HA vs MMW-HA vs LMW-HA: Differences between skin care applications

 

Related Articles:

Micro HA for Cosmetic Applications

How is Sodium Hyaluronate Used For In Cosmetics

Comparative Analysis of Hyaluronic Acid with Different Molecular Weights

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HA4680 Pure Food-Grade Hyaluronic Acid Powder (HAF-H-SC, >1,800 KDa) https://www.stanfordchem.com/food-grade-sodium-hyaluronate.html Thu, 10 Jan 2019 03:22:30 +0000 https://www.stanfordchem.com/?post_type=product&p=6663 Stanford Chemicals Company (SCC) offers Food-Grade High Molecular Weight Hyaluronic Acid for beverage/ supplement applications. We offer pure and organic hyaluronic acid powder in the USA. The hyaluronic acid is non-GMO, Non-animal, kosher, and vegan compliant. High Molecular Weight > 1,800 kDa. CAS Number: 9067-32-7. Samples are available.

 

Related Products: Cosmetic Grade Sodium Hyaluronate​Medical Grade Sodium HyaluronateInjection Grade Sodium HyaluronateCross-linked HA Gel Hyaluronic Acid​

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Pure Food-Grade Hyaluronic Acid Powder (HAF-H-SC) Introduction

Edible hyaluronic acid has some unique properties and functions, such as water retention, lubrication, viscosity, and good biocompatibility, so HA is widely applied to cosmetics, health food, beauty filing operations, pharmaceutics, etc.

The higher the molecular weight and concentration are, the slower the dissolution velocity will be.

Pure Food-Grade Hyaluronic Acid Powder Products

Main Product Item No. Specification
Food Grade

Hyaluronic Acid

HAF-Micro-SC M.W: <5 K Da

Ultra Low Molecular Weight

HAF-Oligo-SC M.W: 5-10 K Da

Low Molecular Weight

HAF-N-SC M.W: 200-600 K Da
HAF-L-SC M.W: 100-1,000 K Da(800 KDa)
HAF-M-SC M.W: 800-1,600 K Da

Middle Molecular Weight

HAF-H-SC M.W: >1,800 K Da

High Molecular Weight

HAF-C-SC Customized Molecular weight

SDS of Food Grade HA:

 

Pure Food-Grade Hyaluronic Acid Powder KDa (HAF-H-SC) Features

Our natural Food-Grade Hyaluronic Acid is manufactured by fermentation with Streptococcus Equi, subsp. Zooepidemicus. It is non-animal sourced, non-GMO, and non-BSE/TSE risk. The raw source includes peptone, glucose, yeast extract, and other raw materials.

We guarantee the HA powder is non-animal derived, Vegan, and adheres to kosher standards. Our production is strictly managed according to ISO 9001 and GMP standards and has been Kosher and Halal certified. It is a safe natural ingredient.

SCC supplies customized Pure Food-Grade Hyaluronic Acid Powder. HAF-C-SC and other tailored HA products have customizable molecular weights. These variants offer versatility and fine-tuned control over their molecular properties for various purposes.

Pure Food-Grade Hyaluronic Acid Powder (HAF-H-SC) Functions

Natural Hyaluronic Acid for dietary supplements offers multiple benefits for joints and the body.

  • Restore skin moisture;
  • Antioxidation;
  • Improve joint health, particularly benefit knees and address osteoarthritis;
  • Improve bowel function and protect the gastric mucosa;
  • Provide hydration, retain moisture, and form a protective barrier on the skin’s surface.
  • Speeds up wound healing: Hyaluronic acid helps wounds heal faster by keeping them moist and reducing inflammation.
  • Improves gum health: Studies show hyaluronic acid can lower the chances of gingivitis and mouth ulcers, helping oral tissue heal.

Pure Food-Grade Hyaluronic Acid Powder (HAF-H-SC) Flow Chart

The sodium hyaluronate(Hyaluronic Acid Sodium salt) manufactured by Stanford Chemicals Company is a fermentation source. See our production flow chart.

Pure Food-Grade Hyaluronic Acid Powder (HAF-H-SC) TDS(Technical Datasheet)

Items Specifications
Appearance White or almost white powder or granules
Identification A. Reaction of alkaline cupric tartrate Positive
B. Reaction of sodium Positive
Particle size Pass through a 60-mesh sieve
pH (5mg/mL solution) 6.0-8.0
Bulk density 0.3-0.6g/cm3
Loss on drying ≤10.0%
Ash ≤13.0%
Limiting viscosity Measured values
Molecular weight >1,800 kDa
Protein ≤0.1%
Heavy metals ≤20ppm
As ≤2ppm
Sodium hyaluronate ≥91.0%
Glucuronic acid ≥44.0%
Bacterial counts ≤500cfu/g
Mold and Yeast ≤100cfu/g
Escherichia coli Negative
Staphylococcus aureus Negative
Salmonella Negative

Pure Food-Grade Hyaluronic Acid Powder (HAF-H-SC) Applications

Hyaluronic Acid for supplement use boosts a wide array of products, supporting both dietary intake and overall health.

Common food: beverage, jelly, dairy products, etc.;

Health food: usually in combination with Collagen,  Vitamins, Chondroitin Sulphate, or GlucoSCCine to make tablets, capsules, or oral liquids these popular forms

 

Related articles on Food Grade Hyaluronic Acid:

Is Hyaluronic Acid Edible?

Food Grade Hyaluronic Acid: Is It Worth Trying?

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HA5227 Pure Injection-Grade Hyaluronic Acid (HA) Powder (HA-EP3.0-SC) https://www.stanfordchem.com/injection-grade-sodium-hyaluronate.html Thu, 10 Jan 2019 03:03:37 +0000 https://www.stanfordchem.com/?post_type=product&p=6657 Pure Injection-Grade HA Powder Molecular Weight 1,800K-2,500KDa Intrinsic Viscosity 2.72-3.53 m3/kg (HA-EP3.0-SC) is widely used for parenteral preparations including intra-articular and intra-ocular preparations, such as OVD, intra-articular injections, intradermal injections for aesthetic correction, anti-adhesive products, etc.

 

Related Products: Food Grade Sodium Hyaluronate, Cosmetic Grade Sodium HyaluronateMedical Grade Sodium Hyaluronate, Cross-linked HA Gel Hyaluronic Acid​

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Pure Injection Hyaluronic Acid (HA) Powder (HA-EP3.0-SC) Introduction

HA-EP3.0-SC, a Pure Injection-Grade Hyaluronic Acid Powder, features a molecular weight ranging from 1,800K to 2,500 KDa and an intrinsic viscosity spanning from 2.73 to 3.53 m³/kg. This specialized variant maintains stringent purity, molecular weight, and other essential characteristics necessary for safe and effective administration via injections in medical, cosmetic, or pharmaceutical contexts. Its various injection-based treatments include dermal fillers, joint injections, and other therapeutic processes.

Pure Injection Hyaluronic Acid (HA) Powder (HA-EP3.0-SC) Specification

Items Specifications
Appearance White or almost white powder or granules
Identification A. Reaction of alkaline cupric tartrate Positive
B. Reaction of sodium Positive
Particle size Pass through a 60-mesh sieve
pH (5mg/mL solution) 6.0-8.0
Bulk density 0.3-0.6g/cm3
Loss on drying ≤10.0%
Ash ≤13.0%
Limiting viscosity 2.73-3.53 m3/kg
Molecular weight 1800-2500 KDa
Protein ≤0.1%
Heavy metals ≤20ppm
As ≤2ppm
Sodium hyaluronate ≥91.0%
Glucuronic acid ≥44.0%
Bacterial counts ≤500cfu/g
Mold and Yeast ≤100cfu/g
Escherichia coli Negative
Staphylococcus aureus Negative
Salmonella Negative

Pure Injection-Grade HA Powder Products

Main Product Item No. Specification
Injection Grade

Hyaluronic Acid

HA-EP1.8-SC M.W: 800K-1,300K Da,

I.V.: 1.44-2.12 m3/kg

HA-EP2.4-SC M.W: 1,300K-1,800K Da;

I.V: 2.12-2.72 m3/kg

HA-EP3.0-SC M.W:1,800K-2,500K Da;

I.V.: 2.72-3.53 m3/kg

HA-EPC-SC Customized Molecular weight

 

SDS of Injection Grade HA

 

Pure Injection Hyaluronic Acid (HA) Powder (HA-EP3.0-SC) Features

Our injection-grade hyaluronic acid is GMP, CEP, and DMF certificated and the factory passed an on-site inspection by the US FDA. Our Injection Grade Hyaluronic Acid is all fermented products, non-animal sources, non-GMO, and non-BSE/TSE risk.

What sets our product apart is its origin. Our pure HA Powder is derived solely from fermentation processes, ensuring it is entirely free from animal sources, non-GMO, and Vegan. Our hyaluronic acid embodies a conscientious choice for those seeking products sourced ethically and naturally, aligning with values of sustainability and purity.

SCC specializes in offering customized injection-grade HAF-C-SC with tailored molecular weights. These HA products cater to specific requirements in various applications. Our HA-EPC-SC signifies a standout Pure Cosmetic-Grade Hyaluronic Acid Powder with uniquely tailored with customizable molecular weights. It is ideal for precise alignment with specific cosmetic formulations.

Pure Injection Hyaluronic Acid (HA) Powder (HA-EP3.0-SC) Functions

  • Viscoelasticity, protecting the corneal endothelium.
  • Lubricating, viscoelasticity, repairing damaged cartilage, inhibition of inflammation, pain relief, etc.
  • Properties of good biocompatibility and degradability of HA and its derivatives.

Pure Injection Hyaluronic Acid (HA) Powder (HA-EP3.0-SC) Applications

  • Dermal fillers: Used in cosmetic and aesthetic applications to reduce wrinkles, and fine lines, and enhance facial tone.
  • Plump lips: A popular ingredient in dermal fillers specifically designed for lip enhancement. When injected into the lips, HA binds with water molecules, adding volume and hydration. This results in fuller, more defined lips.
  • Eye diseases: Used in eye surgeries such as cataract removal and corneal transplants to protect and lubricate the eye.
  • Osteoarthritis: Applied to joints to treat conditions such as osteoarthritis and to relieve fat and pain.
  • Wound care: Used in wound healing and tissue regeneration due to its moisturizing and anti-inflammatory properties.
  • Drug Carrier: Acts as a release agent for controlled drugs, improving efficacy and reducing side effects.
  • Urology: Used to treat bladder pain and constipation, especially in patients with interstitial cystitis.

 

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