Why Chondroitin Sulfate Works for Eye Care

Chondroitin sulfate is suitable for eye care due to its unique biochemical properties and multiple benefits for eye tissues. It has excellent moisturizing abilities, effectively keeping the eye’s mucous membranes hydrated and reducing dryness and discomfort. Additionally, its anti-inflammatory and antioxidant properties help soothe eye inflammation and protect eye tissues from free radical damage. These qualities make chondroitin sulfate an ideal active ingredient in eye drops, especially for managing conditions like dry eye syndrome.

Benefits of Chondroitin Sulfate for the Eyes

• Promotes Cell Repair: It aids in the regeneration and repair of eye cells, boosting the tissue’s self-healing ability.
• Antioxidant Protection: By neutralizing free radicals, it protects eye cells from oxidative stress and delays eye aging.
• Strengthens the Eye Barrier: It enhances the mucous membrane’s barrier function, preventing harmful substances from entering and reducing infection risks.
• Moisturizing and Lubricating: It locks in moisture, keeping the eye’s mucous membranes hydrated.
• Anti-Inflammatory Effects: Its anti-inflammatory properties help reduce redness, swelling, and irritation.

Chondroitin Sulfate vs. Sodium Hyaluronate

Both sodium hyaluronate and chondroitin sulfate are common ingredients in eye drops, excelling in moisturizing and lubrication. However, they differ in specific functions and applications.

Sodium hyaluronate can absorb large amounts of water, providing long-lasting lubrication and high viscoelasticity. It forms a stable protective layer on the eye, reducing discomfort caused by friction. This makes it ideal for dry eye patients needing intense hydration. In contrast, while chondroitin sulfate also offers excellent moisturizing, it focuses more on maintaining the natural hydration of the eye’s mucous membranes. Its moderate viscoelasticity provides a more comfortable lubrication experience.

Additionally, chondroitin sulfate has stronger anti-inflammatory and cell repair benefits, making it stand out. Beyond hydration, it helps reduce inflammation and enhances tissue repair, making it suitable for users who need both hydration and anti-inflammatory support.

Chondroitin Sulfate vs. Ectoine

Ectoine is a natural compatible solute known for its exceptional moisturizing and cell-protecting abilities, widely used in eye drops. Compared to chondroitin sulfate, Ectoine excels in hydration, quickly relieving dryness and maintaining cellular water balance. It protects cells by stabilizing their structure and defending against environmental stressors like dryness and pollution.

However, chondroitin sulfate offers superior repair capabilities. It not only protects cells but also promotes their regeneration and repair. Its anti-inflammatory properties are also more pronounced, effectively reducing eye inflammation. In contrast, Ectoine focuses more on cell protection and stability, with only mild anti-inflammatory effects.

In short, Ectoine provides lightweight hydration, ideal for quick relief from dryness, while chondroitin sulfate offers comprehensive eye care, better suited for long-term use and multi-faceted needs.

Read more: Sodium Hyaluronate vs Ectoine: Which is Better for Skin and Eyes

Other Applications of Chondroitin Sulfate

Beyond eye care, chondroitin sulfate has unique value in several fields:

• Joint Health: As a dietary supplement, it’s widely used to ease joint pain and improve joint function, often combined with glucosamine.
• Skincare: In skincare products, it boosts hydration, promotes skin cell regeneration, and reduces fine lines and wrinkles.
• Cardiovascular Health: Studies show it helps lower blood lipids, improve vascular elasticity, and prevent atherosclerosis.
• Digestive Health: As a dietary fiber, it supports gut health and aids digestion and absorption.
• Oral Care: In oral care products, it improves saliva quality, preventing dry mouth and cavities.

Fig 2. Combined use of hyaluronic acid and chondroitin sulfate for osteoarthritis relief[1]

Stanford Chemical Company (SCC) is an excellent supplier of sodium hyaluronate powder and chondroitin sulfate. In addition, we also provide ectoine powder for cataract surgery eye drops and joints. For more information on these materials, please Get A Quote.

FAQs About Chondroitin

1. Is Chondroitin Sulfate Eye Drops Suitable for Everyone?

Chondroitin sulfate-based eye drops are suitable for most dry eye patients, especially those with dryness caused by prolonged screen use, contact lenses, or dry environments. However, pregnant or breastfeeding women, or those with specific eye conditions, should consult a doctor before use.

2. Are There Side Effects of Using Chondroitin Sulfate Eye Drops?

It’s generally considered safe, with minimal side effects. A few users may experience temporary irritation or mild discomfort, such as a burning sensation or blurred vision, which usually subsides within minutes. If severe discomfort occurs, discontinue use and seek medical attention.

3. How Compatible Is Chondroitin Sulfate with Other Ingredients?

Chondroitin sulfate works well with various moisturizers and anti-inflammatory agents, such as sodium hyaluronate and Ectoine. The synergy between these ingredients provides more comprehensive eye care. Choosing a product with a tailored combination of ingredients can enhance the overall experience.

4. What is chondroitin sulfate in ophthalmology?

Chondroitin sulfate is used in ophthalmology as a moisturizing and anti-inflammatory agent in eye drops, particularly for treating dry eye syndrome and protecting eye tissues.

5. Does chondroitin raise eye pressure?

No, chondroitin sulfate does not raise eye pressure. It is generally safe and used to support eye health.

6. Is chondroitin sulfate an anti-inflammatory?

Yes, chondroitin sulfate has anti-inflammatory properties, helping to reduce inflammation in tissues, including the eyes.

7. Does glucosamine chondroitin affect sleep?

There is no strong evidence that glucosamine chondroitin directly affects sleep. However, individual reactions may vary.

[1] Ma, Y., Yang, X., Jiang, M. et al. Alone or in combination, hyaluronic acid and chondroitin sulfate alleviate ECM degradation in osteoarthritis by inhibiting the NF-κB pathway. J Orthop Surg Res 20, 11 (2025). https://doi.org/10.1186/s13018-024-05411-6

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As a key moisturizing ingredient, sodium hyaluronate is widely recognized. Let’s begin with a brief introduction.

Sodium hyaluronate (the sodium salt form of hyaluronic acid) is a polysaccharide naturally present in human tissues. It is a transparent, viscous substance with excellent moisturizing, lubricating, and anti-inflammatory properties. It is a common ingredient in skincare products and an effective component in eye drops for relieving dry eyes.

So, what is ectoine?

Ectoine is an amino acid derivative found in “Halophile” that thrives in extreme environments. In 1985, German scientist Professor Galinski discovered ectoine in the saline lakes of the Egyptian desert.

It regulates cell osmotic pressure, acting as a natural “protective shield” that enables halophilic bacteria to survive in extreme conditions like high temperatures, high salinity, and intense UV radiation. Biotech companies identified its potential and began producing ectoine (C₆H₁₀N₂O₂) through fermentation. Today, ectoine is used in biomedicine (eye drops, nasal sprays, oral sprays) and skincare products.

Fig 1. Desert salt lake with no grass growing

Sodium Hyaluronate vs Ectoine: Which is Better for Skin

Sodium hyaluronate has been used in skincare products since the 1980s. The exceptional moisturizing ability has made it a star ingredient in the skincare industry. Ectoine, widely adopted by skincare brands since 2019, has gained recognition for its outstanding moisturizing and repair effects, leading to rapid growth in its applications.

Let’s compare the effects of the two

1. Moisturizing

Both ingredients provide moisturizing benefits, but their mechanisms and results differ.

Sodium hyaluronate molecules can absorb hundreds to thousands of times their weight in water. It draws moisture from the environment and locks it in, keeping the skin hydrated. It also forms a breathable hydrating film on the skin’s surface, reducing water evaporation and preventing dryness. What’s more, low-molecular-weight HA can penetrate the dermis, offering deep hydration.

Fig 2. HA for skin

Ectoine’s moisturizing function differs, focusing more on protection and regulation. It binds with water molecules to form a stable hydration shell around cells, creating a protective shield. This shield effectively prevents water loss from skin cells and maintains water balance inside and outside the cells. Additionally, by stabilizing cell membranes and protein structures, ectoine enhances cellular resistance to external stressors like dryness, UV rays, and high temperatures, reducing water loss risks.

Fig 3. The moisturizing principle of Ecdoin

Conclusion: Ectoine’s moisturizing ability leans toward “protective hydration,” without directly absorbing water like sodium hyaluronate. For those focused on hydration, sodium hyaluronate offers more immediate results.

2. Skin Repair:

Sodium hyaluronate is popular in skincare for its skin repair properties. It stabilizes and attracts growth factors (EGF), accelerating cell proliferation, tissue regeneration, and wound healing. It also has anti-inflammatory and soothing effects, reducing damage caused by inflammation.

Ectoine’s repair function is more prominent, especially for sensitive and inflamed skin. When exposed to environmental stressors like high temperatures, UV radiation, hypoxia, heavy metal toxicity, or viral infections, ectoine triggers emergency protective and regenerative responses, helping cells maintain normal physiological activity. Merck data shows that 1.0% Ecdoin can induce a faster stress response, prevent cell damage, and increase the speed of self-healing by 2-3 times.

Conclusion: For skin sensitivity, barrier damage, acne-related breakouts, or sunburn-induced redness, products with ectoine can quickly provide repair and soothing effects.

Key Characteristics Comparison:

Sodium Hyaluronate vs Ectoine: Which is Better for Eyes

Sodium hyaluronate and ectoine are both vital ingredients in eye drops, but their benefits differ in focus.

Sodium hyaluronate is more suitable for individuals with dry eye syndrome, contact lens wearers, or those needing immediate hydration. Its properties allow it to absorb water and form a hydrating film on the eye surface, relieving dryness. Moreover, its natural presence in human tissues ensures high safety with minimal irritation.

Ectoine, on the other hand, is ideal for individuals with eye inflammation, sensitivity, or exposure to harsh environments. By forming a “hydration shell,” ectoine enhances the stability of ocular cells, protecting them from external irritants. It also stabilizes the lipid layer of the tear film, preventing excessive evaporation.

–Synergistic Effects of Sodium Hyaluronate and Ectoine

Studies show that combining ectoine with sodium hyaluronate delivers enhanced synergy in relieving dry eyes. This combination significantly improves water-binding ability, effectively hydrates the eyes, stabilizes the tear film, and reduces tear evaporation. Additionally, it forms a durable hydrating film on the eye surface, firmly adhering to the cornea and ocular surface to provide robust protection against external irritants. Furthermore, this combination is highly effective in alleviating irritation caused by environmental dryness, inflammation symptoms, and itching or burning sensations during allergic reactions.

Stanford Chemical Company (SCC) is an excellent supplier of sodium hyaluronate powder and ectoine powder. In addition, we also provide chondroitin sulfate for cataract surgery eye drops and joints. For more information on these materials, please check out our home page.

The post Sodium Hyaluronate vs Ectoine: Which is Better for Skin and Eyes appeared first on Stanford Chemicals.

Hyaluronic acid (HA) is a high-molecular-weight polysaccharide with repeating disaccharide units of D-glucuronic acid and N-acetylglucosamine. Its salt form, sodium hyaluronate (SH), was initially isolated from the eye’s vitreous body. Sodium hyaluronate has a wide distribution in animal or human tissues, generally located in the extracellular matrix. It has a high concentration in the vitreous humor, aqueous humor, synovial fluid, skin, and umbilical cord.

Sodium hyaluronate is known for its excellent viscoelasticity, unique rheological properties, pseudoplasticity, non-toxicity, and superior biocompatibility.

Fig 1. Artificial tears with hyaluronic acid as the main ingredient

Basis for Sodium Hyaluronate in Ophthalmology Applications

It is highly moisturizing. Sodium hyaluronate can bind water several hundred times its weight, maintaining the ocular surface moisture balance. Its viscoelastic nature allows it to form a stable film on the eye surface, providing lubrication and protection while reducing friction.

As a natural constituent of human tissues, sodium hyaluronate possesses excellent biocompatibility with minimal risk of rejection or irritation. Furthermore, it provides an enhancement in corneal repair and regeneration, reduces inflammation, and soothes discomfort due to environmental stimuli or surgical procedures.

Given these properties, sodium hyaluronate is widely used in ophthalmic products such as artificial tears, surgical viscoelastic fillers, ophthalmic injectables, and corneal repair agents. Its applications range from routine eye care to advanced surgical procedures.

Fig 2. Viscoelasticity of hyaluronic acid

Applications of Sodium Hyaluronate in Eye Health

The uses of sodium hyaluronate in ophthalmology can be roughly divided into two categories. There is ophthalmic viscoelasticity, mainly used in all sorts of ophthalmic surgeries including glaucoma and cataract surgery; another one is eye drops, mainly used in treating dry eyes and corneal burns.

1. Ophthalmic Viscoelastic Agents

1.1 Role in Surgery

Sodium hyaluronate is used as a viscoelastic agent in many eye surgeries. It has a high molecular weight and excellent viscoelasticity, providing mechanical protection for the surgery to take place. Therefore, it maintains structure and prevents tissue collapse or damage caused by surgical instruments.

• Glaucoma Surgery

Sodium hyaluronate protects intraocular tissues, maintains the shape of the anterior chamber, and reduces friction and damage from surgical tools, thus enhancing safety.

• Cataract Surgery

It acts to safeguard the cornea endothelium and to serve as an aid to the implantation of an intraocular lens. It provides a clearer surgical field and minimizes mechanical trauma to the cornea during surgery.

• Trauma Repair Surgery

Sodium hyaluronate serves as a lubricant for the surgical procedure in ocular traumatized patients, inhibits the adhesion of tissues, and provides an optimal environment for healing after surgery.

• Corneal Laser Surgery

The protective film helps prevent excessive drying of tissues and reduces mechanical irritation from surgical instruments.

1.2 Recovery Post-Surgery

Sodium hyaluronate after surgery promotes the repair of tissues, reduces inflammation, and speeds up healing. It keeps the environment moistened to reduce any discomfort for the patients in recovery.

2. Eye Drops

Sodium hyaluronate is used in eye drops for moisturizing and lubrication, relieving dry eyes, protecting the ocular surface, and promoting corneal repair. It is suitable for sensitive people and postoperative care.

2.1 Treatment for Dry Eye

Dry Eye is a chronic condition caused by insufficient tear production or excessive evaporation, leading to symptoms such as dryness, fatigue, and a foreign body sensation. Sodium hyaluronate excels in treating dry eye due to its strong moisturizing properties.

• It forms a uniform protective film on the ocular surface, enhancing tear film stability and preventing tear evaporation.
• Its high water retention alleviates dryness and improves patient comfort.
• It enhances the repair ability of ocular surface cells, preventing more severe damage caused by chronic dryness.

2.2 Corneal Burn Repair

Sodium hyaluronate plays a vital role in treating corneal burns, where the cornea experiences water loss, cell damage, and inflammation. It helps in several ways:

• Moisturizing and Lubricating
• Promoting Cell Regeneration
• Reducing Inflammation

2.3 Daily Eye Care

Sodium hyaluronate-based eye drops are also widely used for daily eye care, especially by individuals who use electronic devices for extended periods or wear contact lenses. These drops effectively relieve discomfort caused by eye strain or insufficient tears, providing long-lasting hydration and lubrication.

Product Recommendations

Stanford Chemical Company (SCC) is one of the leading US-based wholesalers of hyaluronic acid, offering a range of pure hyaluronic acid powders in medical, food, cosmetic, and injectable grades. These cover high, medium, and low molecular weights and also support customization.

The main products in eye health:

References:

Sodium Hyaluronate Used in Anterior Segment Eye Surgery

Hyaluronic Acid: The Ultimate Moisturizer for Dry Eyes

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1. Hyaluronic Acid for Skin: Moisturizing and Anti-Aging

Hyaluronic acid is a component of the dermis layer of the skin, capable of retaining 100 times its weight in water. This is the source of its powerful moisturizing ability. Therefore, using HA can keep the skin hydrated, effectively improving dryness, roughness, and peeling.

For the skin, hyaluronic acid is not just a moisturizer; it also effectively combats aging. This is because HA can fill the gaps within the skin, smoothing out wrinkles and fine lines. Additionally, it increases skin elasticity, making the skin firmer and reducing sagging. As we age, supplementing with HA is a highly effective anti-aging strategy.

Read more:

Hyaluronic Acid Powder: The Acne-Prone Skin Savior

2. Hyaluronic Acid for Facial Contours: Filling Hollows and Smoothing Wrinkles

HA is a primary choice in cosmetic procedures for enhancing facial contours. Hyaluronic acid injections can fill in sunken areas of the face, such as the cheeks, temples, and chin, creating smoother and more defined facial lines. Additionally, it can smooth deep wrinkles, such as nasolabial folds and crow’s feet, lifting sagging facial skin and restoring a youthful, firm appearance.

Fig 1. Hyaluronic Acid for Facial Contours: Before and After

3. Hyaluronic Acid for Lips: Safe Lip Augmentation

Injectable-grade hyaluronic acid is a common method for lip augmentation. By injecting HA, the appearance of the lips can be significantly improved, making them fuller and more defined. Additionally, HA injections can effectively reduce fine lines and wrinkles on the lip surface.

Even without injections, applying HA directly to the lips has benefits. Because of its moisturizing properties, it helps the lips retain moisture, preventing dryness and cracking. Moreover, its anti-inflammatory properties can alleviate symptoms of lip inflammation, reducing redness and discomfort.

Fig 2. Injectable-grade HA on Lips: Before and After

Read more:

Fuller Lips Made Easy: The Power of Hyaluronic Acid

4. Hyaluronic Acid for Wound: Promoting Healing and Reducing Scars

The strong moisturizing capability of hyaluronic acid is not only beneficial for the skin but also accelerates wound healing. It forms a protective film, locking in moisture and preventing the wound from drying and scabbing. Additionally, HA has anti-inflammatory properties, reducing inflammation at the wound site.

Another important role of HA in wound healing is promoting skin regeneration. It facilitates cell migration and proliferation, crucial steps in the healing process. Moreover, HA can reduce scar formation by promoting collagen synthesis, which enhances the strength and elasticity of new tissue, thus minimizing scarring.

Fig 3. The three phases of wound healing

Read more:

Medical Grade Hyaluronic Acid and Wound Healing

5. Hyaluronic Acid for Eyes: Relieving Dryness and Protecting the Cornea

Hyaluronic acid can keep the surface of the eyeball moist, significantly relieving dryness, irritation, and discomfort. Thus, eye drops and gels containing HA are widely used to treat dry eye syndrome and other eye discomforts.

In addition to relieving dry eye symptoms, hyaluronic acid has numerous benefits in eye surgeries. It forms a protective film, preventing dust, bacteria, and other harmful substances from damaging the cornea. In cataract and other intraocular surgeries, hyaluronic acid serves as a filling material, helping maintain the stability of intraocular structures and protecting intraocular tissues. Furthermore, it can be used as a surgical aid, reducing intraoperative damage and promoting postoperative healing.

Read more：

Sodium Hyaluronate for Dry Eyes and How It May Increase Intraocular Pressure

6. Hyaluronic Acid for Joints: Relieving Pain and Delaying Degeneration

Hyaluronic acid has a significant effect on alleviating joint inflammation. It is a crucial component of synovial fluid, providing excellent lubrication. It reduces friction between joint surfaces, protecting cartilage and reducing pain and discomfort during joint movement.

By improving lubrication and reducing pain, HA can enhance joint flexibility and stability, reducing stiffness. Additionally, it protects and repairs joint cartilage, slowing its degeneration.

Fig 4. Anatomy of the healthy and osteoarthritic knee joint[i]

Read more:

Hyaluronic Acid VS. Glucosamine VS. Chondroitin: Which Is Best for Joints?

7. Hyaluronic Acid for Bones: Preventing Osteoporosis

Hyaluronic acid is a key component of the bone matrix, playing an important role in bone health. It provides structural support to bones, promoting the formation and maintenance of the bone matrix.

In the healing process of fractures and bone injuries, HA also plays a crucial role. It promotes the proliferation and differentiation of osteoblasts, accelerating bone regeneration and repair, thus shortening the healing time. Moreover, its anti-inflammatory properties reduce inflammation after bone injuries.

Hyaluronic acid helps prevent osteoporosis by promoting the deposition of minerals (such as calcium and phosphorus) in bones, increasing bone density and strength.

8. Hyaluronic Acid for Hair: Preventing Dryness and Enhancing Strength

Hair that lacks moisture becomes dry and frizzy. Hyaluronic acid, with its moisturizing ability, helps hair retain moisture, making it softer and smoother. Similarly, it keeps the scalp hydrated, preventing dryness and flaking, and promoting a healthy environment for hair growth.

Moreover, HA enhances hair strength and elasticity, reducing breakage and split ends. Its antioxidant properties also benefit hair health by neutralizing free radicals and reducing oxidative stress damage, maintaining the health of the hair.

9. Hyaluronic Acid for Brain: Protecting Nerves

Hyaluronic acid plays a significant role in neuroprotection. It protects nerve cells from external damage, reducing apoptosis and injury. Additionally, hyaluronic acid is an important component of the brain’s extracellular matrix, providing structural support and maintaining the health of the extracellular matrix.

Researchers have noticed the potential of HA in improving cognitive function. By enhancing the health and function of nerve cells, HA may support learning and memory. Its anti-inflammatory and neuroprotective effects could also help reduce age-related cognitive decline.

Fig 5. Different forms of HA scaffolds[ii]

10. Hyaluronic Acid for Teeth: Protecting Gums

Hyaluronic acid significantly protects and repairs gum tissue. It can keep gum tissue hydrated and enhance the barrier function of the gums, preventing bacteria and toxins from invading. Additionally, HA has excellent anti-inflammatory effects. It can inhibit the release of inflammatory factors, alleviating gum inflammation and periodontal disease.

The ability of hyaluronic acid to promote wound healing plays a crucial role in accelerating the healing of oral injuries and post-surgical recovery. Therefore, after tooth extractions or implants, HA can speed up wound healing and reduce postoperative complications.

Conclusion

Hyaluronic acid’s multifaceted benefits span across various aspects of health and beauty, from maintaining skin hydration and enhancing facial contours to promoting joint and bone health. Its unique properties make it an invaluable component in medical treatments and cosmetic applications, improving overall quality of life. As research continues to uncover new potential uses, hyaluronic acid is set to remain a cornerstone of health and wellness.

Stanford Chemical Company (SCC) is an excellent supplier of Sodium Hyaluronate Powder. We provide cosmetic-grade, food-grade, medical-grade, and injection-grade sodium hyaluronate powder. For more information about these materials, please check out our home page.

[i] Fig 4. Anatomy of the healthy and osteoarthritic knee joint. Created via canvas. Source: Smith, Abbi & Sigurbjörnsdóttir. (2022). Hedgehog signaling in bone and osteoarthritis: the role of Smoothened and cholesterol. The FEBS Journal. 290. 10.1111/febs.16440.

[ii] Jensen, G.; Holloway, J.L.; Stabenfeldt, S.E. Hyaluronic Acid Biomaterials for Central Nervous System Regenerative Medicine. Cells 2020, 9, 2113. https://doi.org/10.3390/cells9092113

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The intricate mechanisms of vision rely not only on the complexity of the eye but also on the nutrients that support its function and vitality. Among these vital nutrients, vitamins and hyaluronic acid stand out. They are essential elements in preserving and enhancing eye health. Their collective role extends beyond mere sustenance, delving into maintenance, protection, and the potential improvement of ocular well-being. Let’s have a detailed discussion about their features and uses.

Healthy Vision [1]

Vitamins: Nourishment for Optimal Eye Function

–Vitamin A: The Vision Vitamin

Vitamin A is renowned for its role in vision. It plays a crucial part in the structure of the eye. It contributes to the production of rhodopsin. That is a pigment found in the retina essential for low-light and color vision. Insufficient vitamin A intake may lead to night blindness and other vision impairments.

–Vitamin C: An Antioxidant Shield

As a potent antioxidant, Vitamin C safeguards the eyes from oxidative stress. In this way, it reduces the risk of age-related macular degeneration (AMD) and cataracts. Its presence in the eye’s tissues supports collagen synthesis and helps maintain the cornea and blood vessels.

–Vitamin E: Shielding Against Age-Related Issues

Vitamin E is another powerful antioxidant. It protects cells in the eyes from free radicals, so it potentially reduces the risk of cataracts and AMD. It collaborates with Vitamin C to fortify the eye’s defense against oxidative damage.

Hyaluronic Acid: Moisture and Support for Eye Health

–Hydration and Lubrication

Hyaluronic acid is noted for its moisture-retaining properties. These features contribute significantly to ocular hydration. It supports the maintenance of the eye’s moisture levels and ensures adequate lubrication for optimal comfort and clarity of vision.

–Eye Tissue Health

Beyond hydration, hyaluronic acid supports the health of eye tissues. Found in the vitreous humor and other ocular structures, it aids in maintaining the structural integrity of the eye and may potentially support healing after injuries.

Related reading: Best Companions of Hyaluronic Acid for Skincare

The Synergistic Benefits

Combining these essential vitamins with hyaluronic acid in supplements could offer synergistic benefits for eye health. While a balanced diet is crucial, supplements provide an additional means of ensuring adequate intake, especially for those with specific dietary restrictions or deficiencies.

Other Active Ingredients for Eye Health

Maintaining optimal eye health involves a combination of various nutrients and compounds. Here are some other key active ingredients known for their potential benefits in promoting eye health:

1. Lutein and Zeaxanthin:

• Benefits: These carotenoids are found in high concentrations in the retina and help protect the eyes from harmful high-energy light waves like ultraviolet rays. They may reduce the risk of age-related macular degeneration (AMD) and cataracts.
• Food Sources: Leafy green vegetables, eggs, and certain fruits.

2. Omega-3 Fatty Acids:

• Benefits: DHA (docosahexaenoic acid) is a type of omega-3 fatty acid. It is a major structural component of the retina. Omega-3s may help prevent dry eyes and support overall eye health.
• Food Sources: Fatty fish (salmon, trout, mackerel), chia seeds, flaxseeds, and walnuts.

3. Zinc:

• Benefits: Zinc is essential for the health of the retina and may help prevent AMD and night blindness. It plays a role in transporting Vitamin A from the liver to the retina.
• Food Sources: Meat, dairy products, nuts, and whole grains.

4. Zeaxanthin and Astaxanthin:

• Benefits: Similar to lutein, zeaxanthin, and astaxanthin are carotenoids with antioxidant properties. They may contribute to protecting the eyes from oxidative stress.
• Food Sources: Zeaxanthin can be found in kale, spinach, and collard greens, while astaxanthin is present in salmon, shrimp, and microalgae.

Dosage and Safety

Here are the recommended dosage and upper limits for some common vitamins for adults:

Take the case of Vitamin A (Retinol and Beta-Carotene). Its Recommended Dietary Allowance (RDA) or Daily Adequate Intake (AI) is 700 micrograms (2,333 IU) for women and 900 micrograms (3,000 IU) for men. And the Upper Limit is 3,000 micrograms (about 10,000 IU). [2]

Yet, before introducing new supplements or making significant dietary changes, it’s advisable to consult with an eye care professional or healthcare provider. They can provide personalized advice based on individual needs and any existing eye health conditions. In this way, you can achieve optimal eye health benefits without adverse effects.

Ultimately, a holistic approach that combines a nutritious diet, regular eye check-ups, and appropriate supplementation lays the foundation for clearer, healthier vision and sustained eye wellness throughout life’s journey.

Conclusion: A Visionary Approach to Eye Health

In the intricate symphony of vision, vitamins and hyaluronic acid emerge as key players. Each contributes unique elements crucial for maintaining eye health and function. While these nutrients cannot reverse severe eye conditions, their inclusion in a well-rounded diet or through supplements underscores their importance in supporting ocular vitality and potentially mitigating certain age-related issues.

Explore our comprehensive selection of hyaluronic acid powders crafted for skincare and eye health at Stanford Chemicals Company (SCC). Discover a range of grades and molecular weights tailored to meet your specific business or research needs. Visit our website to find the perfect HA products to elevate your skincare formulations. Send us an inquiry if you are interested.

Reference:

[1] Centers for Disease Control and Prevention (2020, October 1). Keep an Eye on Your Vision Health. Centers for Disease Control and Prevention. Retrieved December 7, 2023, from https://www.cdc.gov/visionhealth/resources/features/keep-eye-on-vision-health.html

[2] Harvard T.H. Chan School of Public Health (2023, March 7). Vitamins and Minerals. Harvard T.H. Chan School of Public Health. Retrieved December 7, 2023, from https://www.hsph.harvard.edu/nutritionsource/vitamins/

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Hyaluronic acid (HA) has gained significant attention in the beauty industry for its remarkable hydrating and anti-aging properties. It has become a staple ingredient in skincare products, known for its ability to plump and moisturize the skin. However, the benefits of HA extend far beyond the realm of beauty. This versatile substance also plays a vital role in joint health and overall well-being. Let’s dive into the versatility of hyaluronic acid and discover its diverse applications.

Understanding Hyaluronic Acid

Hyaluronic acid is a type of carbohydrate molecule that is naturally produced by the body. It is found in various tissues and fluids, such as the skin, joints, and eyes. HA is known for its ability to retain moisture, which helps to keep tissues well-lubricated and moisturized. It has various applications in the medical, cosmetic, and pharmaceutical industries.

Chemical Structure of HA

Applications of Hyaluronic Acid

1.    The Beauty of Hyaluronic Acid

In the realm of beauty, hyaluronic acid has gained a reputation as a holy grail ingredient. Its unique ability to retain moisture makes it a powerful hydrator for the skin. HA molecules can hold up to 1,000 times their weight in water, helping to replenish and maintain optimal hydration levels. By attracting and locking in moisture, it plumps the skin, smooths out fine lines and wrinkles, and enhances overall radiance. Therefore, HA becomes a key ingredient in serums, moisturizers, and facial masks, providing a boost of hydration and promoting a youthful complexion.

2.    Dermal Fillers and Facial Contouring

Hyaluronic acid dermal fillers are another HA product in the field of cosmetics. They are used to restore lost volume, enhance facial contours, and diminish the appearance of wrinkles and folds. By injecting them beneath the skin’s surface, a skilled professional can sculpt and rejuvenate the face, providing natural-looking results. Dermal fillers offer a non-surgical solution for those seeking facial rejuvenation and enhancement. So, most individuals can resume their regular activities immediately after the treatment.

3.    Joint Health and Hyaluronic Acid

Beyond its beauty benefits, hyaluronic acid plays a critical role in maintaining healthy joints. It is naturally present in the synovial fluid that lubricates and cushions the joints. HA acts as a shock absorber, reducing friction and ensuring smooth movement. With age or certain medical conditions, its production in the joints may decrease, leading to joint stiffness, discomfort, and limited mobility. In these cases, HA injections can be administered directly into the affected joint to restore lubrication, reduce pain, and improve joint function. These injections have become a popular treatment option for individuals with conditions such as osteoarthritis.

4.    Eye Health and Lubrication

Medical-grade HA is also used in ophthalmology for its lubricating properties in the form of eye drops. These eye drops help alleviate symptoms of dry eyes by providing a protective and moisturizing layer on the surface of the eyes. The hyaluronic acid forms a barrier that prevents moisture loss, reduces friction, and soothes dryness, thereby improving overall eye comfort and health.

5.    Wound Healing and Tissue Repair

Hyaluronic acid’s versatile nature extends to the realm of wound healing and tissue repair. HA plays a crucial role in the body’s natural healing processes. It promotes cell migration, collagen synthesis, and angiogenesis (the formation of new blood vessels), which are essential for efficient wound healing. By providing a favorable environment for tissue regeneration, this natural substance supports the body’s ability to heal wounds, reduce scarring, and promote overall tissue repair.

Conclusion

Hyaluronic acid is undoubtedly a versatile and multi-faceted compound. Its hydrating and anti-aging properties make it a go-to ingredient in the beauty industry, helping individuals achieve plump and youthful skin. Moreover, this acid plays a vital role in joint health, wound healing, eye lubrication, and facial contouring. Its ability to provide hydration, lubrication, and tissue repair makes it a valuable asset in various medical and cosmetic applications. Whether you’re seeking a beauty boost or joint relief, hyaluronic acid proves to be an exceptional ally in promoting overall well-being.

Stanford Chemicals Company (SCC) offers quality hyaluronic acid powder for skin care and joint health applications. Both cosmetic-grade HA and medical-grade HA are available. You can check our website for more information. Hope that you can find the perfect HA products for your business or research.

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Dry eyes can be a bothersome and uncomfortable condition that affects many people. Whether caused by environmental factors, aging, or underlying health conditions, finding relief for dry eyes is essential for maintaining eye health and comfort. While eye drops and other treatments are commonly used, there’s a powerful ingredient that has emerged as the ultimate moisturizer for dry eyes: hyaluronic acid (HA). Let’s explore how hyaluronic acid can provide much-needed hydration and relief for dry eyes.

Human Eyes

What Is Dry Eye Syndrome?

Dry eye syndrome occurs when there is insufficient moisture or lubrication on the surface of the eyes, which can lead to symptoms such as itching, burning, redness, and a gritty sensation. Dry eyes can be caused by various factors, including decreased tear production, excessive tear evaporation, or an imbalance in the composition of tears. It’s a condition that can significantly impact daily life and overall eye health.

Dry Eye Syndrome [1]

How Hyaluronic Acid Is Used to Relieve Dry Eyes?

Hyaluronic acid is a natural humectant that alleviates dry eye syndrome in the following ways.

–The Hydrating Power of Hyaluronic Acid

Hyaluronic acid is a natural substance in the body with a remarkable ability to retain moisture. It can hold up to 1,000 times its weight in water, making it an exceptional hydrating agent. When applied topically to the eyes, HA forms a protective barrier on the surface of the eyes, preventing moisture loss and promoting hydration. This helps to alleviate dryness and discomfort, providing relief to individuals suffering from dry eyes.

–Restoring Tear Film Balance

The tear film is a thin layer that covers the surface of the eyes, keeping them moisturized and protected. In individuals with dry eyes, there is often an imbalance in the tear film composition, resulting in inadequate lubrication. HA helps restore this balance by enhancing the quality and quantity of tears. It promotes the production of high-quality tears that effectively coat the eyes, reducing friction and soothing dryness.

–Soothing and Calming Irritation

Dry eyes often come with symptoms of irritation, such as redness, itching, and a burning sensation. Hyaluronic acid has soothing and anti-inflammatory properties that can help alleviate these discomforts. By moisturizing the eyes and reducing inflammation, HA provides relief and helps calm irritated eyes. Its gentle and non-irritating nature makes it suitable for those with sensitive eyes.

–Easy Application and Compatibility

Using hyaluronic acid for dry eyes is simple and convenient. It is available in various forms, including eye drops, gels, and ointments. Eye drops containing hyaluronic acid can be applied directly to the eyes for quick relief. These formulations are compatible with contact lenses, allowing individuals to experience the benefits of hyaluronic acid while wearing their lenses. Whether you’re at home, at work, or on the go, hyaluronic acid eye drops can be easily incorporated into your daily routine.

Related reading: How to Choose Eye Drops?

–Long-Lasting Hydration

One of the significant advantages of hyaluronic acid for dry eyes is its long-lasting hydration. Unlike traditional eye drops that provide temporary relief, hyaluronic acid creates a reservoir of moisture that gradually releases over time. This means that the eyes stay hydrated for longer periods, reducing the need for frequent reapplication and providing sustained comfort throughout the day.

Conclusion

In a word, hyaluronic acid is a game-changer when it comes to moisturizing dry eyes. Its hydrating properties, ability to restore tear film balance, and soothing effects make it the ultimate moisturizer for dry eyes. If you’re experiencing the discomfort of dry eyes, consult with an eye care professional to determine if hyaluronic acid eye drops or other formulations may be suitable for your needs. Embrace the power of hyaluronic acid and enjoy the relief and comfort of well-hydrated eyes.

Stanford Chemicals Company (SCC) is a reliable supplier of hyaluronic acid of different grades and molecular weights. For more information, check our homepage.

Reference:

[1] Yazdani M, Elgstøen KBP, Rootwelt H, Shahdadfar A, Utheim ØA, Utheim TP. Tear Metabolomics in Dry Eye Disease: A Review. International Journal of Molecular Sciences. 2019; 20(15):3755. https://doi.org/10.3390/ijms20153755

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Sodium hyaluronate, the salt form of hyaluronic acid, is a naturally occurring polysaccharide group of sugar in the human body. It is a popular ingredient in skincare and cosmetics due to its ability to hydrate and plump the skin. This sodium salt also has a wide range of applications in the medical field, particularly in anterior segment eye surgery. In this article, we will discuss the utilization and benefits of sodium hyaluronate in anterior segment surgery.

What Is Anterior Segment Surgery?

Anterior segment surgery involves operating on the structures in the front of the eye, such as the cornea, iris, and lens. These surgeries can range from cataract removal to corneal transplants. It is crucial to maintain the clarity of the cornea and the surrounding tissues to ensure a successful outcome. Sodium hyaluronate can play an essential role in achieving this.

Human Eyes

Benefits of Sodium Hyaluronate Employed in Anterior Segment Surgery

Sodium hyaluronate is a natural substance largely found in the extracellular matrix of connective tissues. It is in the aqueous humor and the vitreous, and it forms a protective coating on the corneal endothelium. Sodium hyaluronate and other viscoelastic substances, such as chondroitin sulfate and collagen, have been used for eye surgeries since the 1970s. These viscoelastic agents are used to protect and maintain the shape of the eye during surgery. They help create space for the surgeon to work and prevent damage to delicate structures as well.

Eye Anatomy

–Maintaining A Deep Anterior Chamber

The primary benefit of using this salt as a viscoelastic agent is its ability to maintain a stable anterior chamber during the operation. The anterior chamber is the fluid-filled space between the cornea and the iris, and maintaining its stability is essential for successful surgery. Sodium hyaluronate can help stabilize the anterior chamber by providing a cushioning effect and preventing the collapse of the chamber. Therefore, it is easier to separate and maneuver these tissues, and the damage to the cornea and other tissues can be minimized.

–Protecting the Corneal Endothelium

Besides, the excellent lubricating properties of sodium hyaluronate can help reduce the risk of damage to the corneal endothelium during surgery. The corneal endothelium is a layer of cells that lines the back of the cornea, which is crucial for maintaining corneal clarity. Damage to the corneal endothelium can result in complications such as corneal edema and decreased vision. If it got scratched, there would be serious vision problems because all light passes through it and any defect might lead to a “blind spot”.

–No Adverse Effect

Sodium hyaluronate is a substance widely present in the human body, and there is no report on its adverse effects. So, it is considered to have no adverse effects and is safe to take. It is also biocompatible, meaning it is well-tolerated by the body and does not cause adverse reactions. Moreover, sodium hyaluronate can be easily absorbed by the body and does not require removal after surgery.

Sodium hyaluronate is available in various forms, including gels, solutions, and ointments. The choice of form depends on the specific needs of the surgery and the surgeon’s preference. There is a variety of medical-grade sodium hyaluronates on our website. Send us an inquiry if you are interested.

Related reading: Medical-grade Sodium Hyaluronate Guide 2023: Functions & Applications

Examples of Sodium Hyaluronate Used in Anterior Segment Surgery

You can find sodium hyaluronate as a surgical aid during ophthalmic surgeries including cataract extraction, corneal transplant, glaucoma infiltration, and intraocular lens implantation. With sodium hyaluronate products, the safety and reliability of anterior segment eye surgeries have been improved.

–Cataract Operations

Sodium hyaluronate was used as a surgical device for two cataract surgeries: intracapsular cataract extraction (ICCE) with corneoscleral incision and corneal incision. There were 80 patients divided in two groups. The first group used sodium hyaluronate products, while the control group employed a balanced salt solution (BSS) instead. It was proven that this sodium salt has a protective effect on the cornea and no side effects, such as intraocular pressure or inflammatory reaction, have been observed. [2]

–Intraocular Foreign Body (IOFB)

Diverse surgical instruments have been employed to remove intraocular foreign bodies (IOFBs). A 38-year-old healthy man suffered from a glass IOFB in the left eye after a glass exploration. Medical-grade sodium hyaluronate gel was used to remove the IOFB, which could avoid damage to the retina and make it easier to grasp the flat glass fragment. [3]

Conclusion

In a word, sodium hyaluronate is a useful tool in anterior segment surgery. Its viscoelastic properties can help maintain a stable anterior chamber and protect delicate structures during surgery. Its lubricating properties can reduce the risk of damage to the corneal endothelium, and its biocompatibility makes it a safe choice for use in surgery. If you are undergoing anterior segment eye surgery, be sure to discuss the use of sodium hyaluronate with your surgeon and learn about how it can benefit your surgery.

Stanford Chemical Company is a leading supplier of medical-grade sodium hyaluronate. Cosmetic grade, food grade, and injection grade are also available. Check our homepage to look for the perfect sodium hyaluronate products for your projects.

Reference:

[1] Souto, Eliana B. & Zielińska, Aleksandra & Luis, M. & Carbone, Claudia & Martins-Gomes, Carlos & Souto, Selma & Silva, Amélia. (2019). Uveal melanoma: physiopathology and new in situ-specific therapies. Cancer Chemotherapy and Pharmacology. 84. 10.1007/s00280-019-03860-z.

[2] Åke S. Holmberg, Bo T. Philpson, (1984). Sodium Hyaluronate in Cataract Surgery: I. Report on the Use of Healon® in Two Different Types of Intracapsular Cataract Surgery. Ophthalmology, 91(1), 45-52. https://doi.org/10.1016/S0161-6420(84)34341-X.

[3] Zhang J, Mao H, Zou X, Deng G. (2020). Use of medical sodium hyaluronate gel in surgical removal of a glass intraocular foreign body. Journal of International Medical Research, 45-52. https://doi.org/10.1177/0300060520956856.

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Sodium hyaluronate has been a buzzword for years because of its water retention effect in the cosmetic sector. However, this natural humectant also stands out for its protective functions in the medical field. Here, this article is going to discuss the medical uses of sodium hyaluronate. Hope that you can have a better understanding of how medical-grade sodium hyaluronate is employed in the treatment and pain relief of joints, eyes, etc.

Medical-grade Sodium Hyaluronate

What Is Medical-grade Sodium Hyaluronate?

–Basics

Sodium hyaluronate is a natural substance found in the human body. This sodium salt is a visco-elastic long-chain polymer of sugar units of Na-glucuronate-N-acetylglucosamine. It is widely present in the extracellular matrix of connective and neural tissues in our body. Sodium hyaluronate is also involved in cell differentiation, wound healing, and inflammation.

–Functions

Sodium hyaluronate plays an essential part in modulating the interactions inside our body. First, medical-grade sodium hyaluronate could form a viscoelastic solution, which serves as a protective barrier for our tissues and cells. The solution could also absorb mechanical stress. Last, this sodium salt is thought to provide nutrients to injured cells to promote tissue repair and cell growth. With these notable properties, medical-grade sodium hyaluronate is applied to treat arthritis, cataract, dry eye syndrome, and other diseases.

What Are the Medical Uses of Sodium Hyaluronate?

–Sodium Hyaluronate for Intra-articular Injection

Sodium hyaluronate is commonly employed to reduce the pain of osteoarthritis and other joint illnesses for its lubricating and protective functions.

Osteoarthritis

Sodium hyaluronate is a component of the joint fluid that lies between your bones and cartilage. The fluid acts as a lubricant and absorbs shock in the joint, so you can move smoothly. Nevertheless, people with osteoarthritis have less hyaluronic acid and less joint fluid, causing pain, swelling, stiffness, and other uncomfortable symptoms. If you have these symptoms, you just need an injection of sodium hyaluronate to recover the viscoelasticity of the articular fluid and stimulate new fluid production.

–Sodium Hyaluronate to Cure Eye Diseases

Sodium hyaluronate is also extensively used in ophthalmic surgeries.

You can use medical-grade sodium hyaluronate to make artificial tears to alleviate dry eye syndrome. These artificial tears can form stable water film on the ocular surface to moisturize your eyes for a long time. Therefore, you can be saved from redness, itchy eyes, and blurred vision.

Eye Drops

Sodium hyaluronate is one of the most popular ophthalmic viscoelastic devices (OVDs) used in cataract surgery. It generates a deep chamber and protects the corneal tissues. Sodium hyaluronate acts as an OVD in corneal transplant, intraocular lens implantation, and retina attachment surgery as well.

Related reading: Which Eye Surgeries Get Use of Hyaluronic Acid Preparations?

–Other Medical Uses of Sodium Hyaluronate

There are many more medical uses of sodium hyaluronate listed below.

• Anti-adhesive Products: Medical workers employ anti-adhesion products containing sodium hyaluronate to treat adhesions that frequently take place after abdominal surgery.
• Dermal Injection: Sodium hyaluronate is an ideal option for dermal fillers that are injected to fill out wrinkles and obtain a more youthful appearance.
• Topical Preparations: It is used to protect skin ulcers, burns, or irritations. The salt forms a protective layer over the affected area.
• Wound-healing Products: An optimal wound dressing can be made from medical-grade sodium hyaluronate to prevent infection and inflammation.

Related reading: Best Skincare Products: What is Sodium Hyaluronate Powder?

Conclusion

Medical-grade sodium hyaluronate found lots of applications in osteoarthritis, eye surgeries, and dry eye syndrome due to its lubricating and protective features. Stanford Chemicals Company (SCC) provides high-quality sodium hyaluronate of different molecular weights and grades. For more information concerning medical-grade sodium hyaluronate, please visit our homepage.

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Sodium Hyaluronate for Skin

Sodium Hyaluronate can be found abundantly in the dermis, helping skin retain its moisture.

The skin remains hydrated and the surface is supple when the skin contains adequate concentrations of hyaluronic acid.

Sodium Hyaluronate for Joint

Joint fluid and articular cartilage contain hyaluronic acid at high concentrations. HA serves as a lubricant (preventing bone-to-bone friction) and as a cushion. This function allows our joints to move smoothly.
A joint function-improving agent with hyaluronic acid as its active pharmaceutical ingredient is a prescription drug.

Sodium Hyaluronate is injected into joints to treat patients suffering from knee osteoarthritis, periarthritis of the shoulder (also known as frozen shoulder syndrome), and knee pain from rheumatoid arthritis. Hyaluronic acid has been reported to have anti-inflammatory and pain-relieving effects in such uses.

Sodium Hyaluronate for Eyes

The vitreous body contains high concentrations of Sodium Hyaluronate, which provides cushioning and plays a role in maintaining the shape of the eyeball.

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